Antiseptics and Disinfectants Flashcards

1
Q

antiseptic

A

substance applied to living tissue that inhibits growth and development of microorganisms

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2
Q

disinfectant

A

substance applied to inanimate objects to eliminate pathogenic microorganisms

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3
Q

germicide

A

substance used to destroy infective microorganisms

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4
Q

cleanser

A

substance that aids in physical removal of foreign material

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5
Q

sanitizer

A

substance that reduces the number of bacteria to levels considered safe according to public health interpretations

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6
Q

sterilization

A

complete destruction of all forms of microbial life

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7
Q

effectiveness dependent on

A

agent, microorganism, host

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8
Q

modes of action

A

adsorption, diffusion, altered permeability of microorganism

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9
Q

in vitro testing of antimicrobials

A

comparison to phenol

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10
Q

physical agents

A

heat (moist and dry), light

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11
Q

light can kill

A

gram negative and nonsporulating bacteria

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12
Q

bacteriostatic pH

A

3-6

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13
Q

bacteriocidal pH

A

<3

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14
Q

______ weak acids penetrate cells and disrupt cell membranes

A

lipid-soluble

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15
Q

inorganic acid used as antiseptic

A

boric acid

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16
Q

organic acid used as antiseptic

A

acetic, benzoic, oticlens (salicylic, malic, benzoic)

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17
Q

antifungal acids

A

propionic acid and undecylenic acid

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18
Q

alkali most effective pH

A

> 9

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19
Q

alkali concern

A

irritating to skin and mucous membranes

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20
Q

surfactant mechanism

A

decrease surface tension of aqueous solutions

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21
Q

anionic surfactant

A

soap

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22
Q

cationic surfactant

A

quaternary ammonium compounds

23
Q

anionic surfactant inactivated by

A

cationic surfactant

24
Q

quaternary ammonium compounds inactivated by

A

serum and tissue debris

25
Q

cationic surfactants better at

A

disinfecting

26
Q

vet and kennel disinfectant type

A

quaternary ammonium compound

27
Q

% alcohol used for aseptic preparation of surgeon’s hands

A

80

28
Q

iodine vs chlorine affected by organic matter

A

iodine less affected

29
Q

iodophor

A

iodine combined with surfactant, polymer, detergent, wetting agent, solubilizer

30
Q

povidone-iodine

A

polyvinylpyrrolidone and iodine, sustained release of iodine

31
Q

chlorine use

A

surfaces, wounds, therapeutic shampoo for pyoderma

32
Q

Dakin’s solution

A

0.5% sodium hypochlorite, used for wounds

33
Q

phenols used

A

hexachlorophene, chlorophenols

34
Q

hexachlorophene spectrum

A

gram-positive

35
Q

hexachlorophene vs povidone-iodine and chlorhexidine

A

less effective

36
Q

hexachlorophene toxicity

A

neurotoxicity

37
Q

chloroxylenol vs chlorhexidine

A

less effective, no difference in wound infection rate

38
Q

triclosan

A

in consumer products and suture material

39
Q

heavy metals mechanism

A

form toxic salts that interferes with bacterial enxymes

40
Q

heavy metals used in vet med

A

silver compounds

41
Q

hydrogen peroxide action

A

brief action, not disinfecting

42
Q

gas plasma sterilization

A

59% hydrogen peroxide in electromagnetic field

43
Q

accelerated hydrogen peroxide

A

hydrogen peroxide combined with surfactants and other to increase action

44
Q

azo dye spectrum

A

gram negative

45
Q

basic dye spectrum

A

gram positive

46
Q

methenamine

A

PO, converts to formaldehyde in acidic urine

47
Q

cold sterilization

A

glutaraldehyde

48
Q

triclosan types

A

ether and phenol

49
Q

chlorhexidine length of action

A

long-lasting residue

50
Q

chlorhexidine toxicity

A

low, eyes

51
Q

chlorhexidine solution

A

0.05% in sterile water

52
Q

chlorhexidine gluconate in ethyl alcohol use

A

surgery prep

53
Q

polyhexamethylene biguanide effective against

A

MRSA