Antiseptics and Disinfectants Flashcards
antiseptic
substance applied to living tissue that inhibits growth and development of microorganisms
disinfectant
substance applied to inanimate objects to eliminate pathogenic microorganisms
germicide
substance used to destroy infective microorganisms
cleanser
substance that aids in physical removal of foreign material
sanitizer
substance that reduces the number of bacteria to levels considered safe according to public health interpretations
sterilization
complete destruction of all forms of microbial life
effectiveness dependent on
agent, microorganism, host
modes of action
adsorption, diffusion, altered permeability of microorganism
in vitro testing of antimicrobials
comparison to phenol
physical agents
heat (moist and dry), light
light can kill
gram negative and nonsporulating bacteria
bacteriostatic pH
3-6
bacteriocidal pH
<3
______ weak acids penetrate cells and disrupt cell membranes
lipid-soluble
inorganic acid used as antiseptic
boric acid
organic acid used as antiseptic
acetic, benzoic, oticlens (salicylic, malic, benzoic)
antifungal acids
propionic acid and undecylenic acid
alkali most effective pH
> 9
alkali concern
irritating to skin and mucous membranes
surfactant mechanism
decrease surface tension of aqueous solutions
anionic surfactant
soap