Antiretrovirals

Question 1

5 groups of antiretroviral?

Answer 1

Nucleoside reverse transcriptase inhibitors (NRTI)

Nucleotide reverse transcriptase inhibitors (NtRTI)

Non nucleoside reverse transcriptase inhibitors (NNRTI)

Protease inhibitors (PI)

Integrase inhibitors (INSTI)

Question 2

NRTI?

Answer 2

LAZE

Lamivudine
Abacavir
Zidovudine
Emtricitabine (m3c tabine)

Question 3

NtRTI?

Answer 3

TAF
TDF

Tenofovir alafenamide fumarate

Tenofovir disoproxil fumarate

Question 4

NNRTI

Answer 4

RED - Rilpi efa Dora (virine)

Rilpivirine
Efavirenz
Doravirine

Question 4

Protease inhibitors

Answer 4

LARD
Lopi Ate Rito Dinner (navir)

Lopinavir
Atazanavir
Ritonavir
Darunavir

Question 5

Integrase inhibitors

Answer 5

RBC but RBD (gravir)
Ralte bi(c)t dolu

Raltegravir
Bictegravir
Dolutegravir

Question 6

Antiviral with Renal and bone warning?

Answer 6

Tenofovir disoproxil fumarate

Question 7

Precautions for Abacavir?

Answer 7

Check HLA B5701, give if negative

Give if estimated 10 year risk of CVD is <10%

Question 8

Discontinuation of which antiretroviral in people with coinfection of HIV and hep B leads to severe acute exacerbation of hepatitis?

Answer 8

TDF/ TAF

Lamivudine/ Emtricitabine