Antipsychotics

Question 1

Lurasidone (2nd gen) (atypical)

Answer 1

SE: NMS, suicidal thoughts, seizures, drowsiness

PT edu: avoid driving/ other motor activities d/t drowsiness

Indication: depressive episode BPD I

CI: QT prolongation, recent MI

Precaution/ monitor: blood sugar, liver; kidney levels, ECG

Question 2

Typical (1st gen) (3)

Answer 2

-chloprazomine (Thorazine)
-haloperidol (Haldol)
-fluphenazine (prolixin)

Question 3

What does atypical antipsychotics focus on?

Answer 3

Block specific serotonin receptors

Question 4

Atypical ADR and SE

Answer 4

-eps: affects muscles; tremors
-muscle spasm: dystopia
-akathesia: restlessness
-tardive dyskenia: smacking lips; sticking out tongue

Question 5

Ziprasidone (atypical)

Answer 5

ADR: Qt prolongation/ tornadoes de pointes

NI/ monitor: cardiac monitoring

Question 6

Ziprasidone (atypical) SE & pt EDU

Answer 6

SE: c/d/n, nms, sjs

PT edu: do not stop abruptly, notify hcp for LOC, dizziness, palpitations, sexual dysfunction, and menstrual abruption