antidepressants Flashcards
Antidepressants SSRI’s & SNRI’s
Side Effects
(5)
weight changes
insomnia
agitation
headache
sexual dysfunction
Antidepressants SSRI’s & SNRI’s
Adverse Reactions
- SEROTONIN SYNDROME
elevated VS, hyperrreflexia, change in mental status, cyoclonus, restlessness
Antidepressants SSRI’s & SNRI’s
Treatment
(3)
d/c offending agent
cooling blanket -> reduce temp
meds to block serotonin receptors
Antidepressants
Heterocyclics & SNRI’s
Interactions
concomitant use of MAOI’s result in serious fatal effects resembling neuropletic malignant syndrome.
Co-administration is contraindicated
increase effects of haloperidol, clozapine & desipramine when use concom w/ venlafaxine. of venlafaxine w/ cimetidine.
increase risk of liver injury w/ concomitant use of alcohol & duloxetine
Antidepressants Heterocyclics
Side Effects (6)
Blurred vision
constipation
urinary retention
orthostatic hypotension
reduction of seizure threshold
tachycardia, arrhythmias
Antidepressants MAOI’s
monoamine oxidase inhibitors
isocarboxazide (marplan)
phenelzine (Nardil)
tranylcypromine (pamate)
selegine (eldepryl & emsan)
*AVOID high in tyramine
High in Tyramine
age cheese, wine;beer, chocolate; colas, coffee; tea, diet pills, yeast, cold remedies, precessed meats, liver, soy sauce, raisins, yougurt/sourcream