Antipsychotics

Question 1

Risks associated with antipsychotics

Answer 1

Neuroleptic malignant syndrome.
Increasing QTc interval

Question 2

Adverse effects of antipsychotics

Answer 2

Extra pyramidal side effects.
Metabolic syndrome
Postural hypotension
Hyperprolactinaemia

Question 3

First generatio antipsychotics

Answer 3

Flupentixol, haloperidol, zuclopenthixol, chlorpromazine, sulpriride

Question 4

What is used for rapid tranquilisation

Answer 4

Haloperidol IM or Olanzapine IM

Question 5

Second generation antipsychotics

Answer 5

Amisulpride, risperidone, paliperidone, olanzapine, quetiapine

Question 6

Third generation antipsychotics

Answer 6

Aripiprazole, Lurasidone, Clozapine

Question 7

What are the extrapyramidal side effects

Answer 7

Dystonias, Akathesia, Parkinsonism, Tardive dyskinesia

Question 8

What are depot antipsychotics

Answer 8

Release antipsychotic over 1-12 weeks, atypicals

Question 9

Which medications are given by depot

Answer 9

Atypicals - Risperidone, paliperidone, olanzapine, aripiprazole

Question 10

Which medication is most effective in treatment resistant Sz

Answer 10

Clozapine

Question 11

What are the risks of taking clozapine

Answer 11

Can cause neutropenia and agranulocytosis