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PSYCHIATRIC > ANTIPSYCHOTICS > Flashcards

ANTIPSYCHOTICS Flashcards

1
Q

Chlorpromazine, Thioridazine

A

1st Generation- Low Potencty Agent

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2
Q

Fluphenazine, Haloperidol

A

1st Generation- High Potency

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3
Q

Low Potency= __ sedation + __ AcH + __ EPS

A

HIGH sedation, HIGH AcH, LOW EPS

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4
Q

High Potency= __ sedation + __ AcH + __ EPS

A

LOW sedation, LOW AcH, HIGH EPS

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5
Q

1st generation effects which NT?

A

dopamine

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6
Q

How long does it take for antipsychotics to take effect?

A

2-6 weeks

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7
Q

1st Generation used for what sx

A

positive sx

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8
Q

1st Generation- AE

A

EPS, sedation, orthostatic HT, sexual dysfunction, weight gain, seizure-vulnerability, tardive dyskinesia

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9
Q

EPS Sx

A

Dystonia (contraction of muscles), Akathisia (restlessness/inability to stay still), Psuedoparkinsonism (tremors, weak gait, reduced facial expressiveness)

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10
Q

Tx for EPS

A

Diphenhydramine, Benzotropine

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11
Q

Clozapine, Risperidone, Paliperidone, Olanzapine, Ziprasidone, Lurasidone, Quetiapine

A

2nd Generation Antipsychotics

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12
Q

2nd Generation Tx used for what Sx

A

positive & negative

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13
Q

2nd Generation- AE

A

sedation, weight gain, sexual dysfunction

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14
Q

2nd Generation increased risk for what ___ syndrome

A

metabolic syndrome

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15
Q

Sx of Metabolic Syndrome

A

weight gain, insulin resistance, increased blood glucose, dyslipidemia, increased risk for diabetes, HT, cardiovascular disease

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16
Q

Clozapine increases risk for what

A

severe neutropenia (<500/UL)

17
Q

Risperidone CI in who

A

dementia patients

18
Q

What do you monitor in Ziprasidone?

A

BP & QT waves

19
Q

Anticholinergic Toxicity- Sx

A

dilated pupils, confusion, urinary retention, reduced peristalsis, altered mental statues

20
Q

Anticholinergic Toxicity- Tx

A

Hold all medication
NTP
Cooling agents

21
Q

Physostigmine used to reverse what

A

Anticholinergic Toxicity

22
Q

What do you evaluate when psychosis is worsening?

A

Anticholinergic Toxicity

23
Q

Neuroleptic Malignant Syndrome is seen in which medication?

A

Haloperidol

24
Q

NMS- Sx

A

muscle fidgety, fever, reduced consciousness, sweating, altered mental status

25
Q

NMS- Tx

A

hold all antipsychotics
NTP
Cooling agents
maintain hydration

26
Q

Bromocriptine & Dantrolene

A

NMS- Tx medication for muscle rigidity

27
Q

What is neutropenia?

A

dangerously low WBC

28
Q

Neutropenia- Sx

A

fever, flu-like Sx, sore throat, prone to more infections

PSYCHIATRIC (5 decks)

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