Antipsychotic drugs Flashcards
1
Q
Pathophysiology of schizophrenia
A
increased activation of dopamine pathway via increased number of dopamine receptors
2
Q
What is the mechanism of action of most anti-psychotic drugs?
A
They are usually specific for and antagonise the D2 receptor
3
Q
What other receptors do D2 receptor antagonists affect?
A
5HT2; muscarinic; histamine; a1 adrenoceptors
4
Q
A
