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Psych > Antipsychotic Agents > Flashcards

Antipsychotic Agents Flashcards

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1
Q

Antipsychotic ACTION

A

block postsynaptic dopamine receptors

inhibit dopamine-mediated transmission of neural impulses

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2
Q

Antipsychotic INDICATIONS

A

schizo
bipolar mania
antiemetics
intractable hiccoughs

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3
Q

Conventional/typical/1st gen medicines

A

Phenothiazines (thorazine, Prolixin)
Thioxanthenes (Navane)
Dibenzoxazepnes (Loxitane)
Haloperidol (HALDOL)

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4
Q

Antipsychotic CONTRA

A 
comatose
CNS depression
blood dyscrasias
parkinsons
glaucoma
dementia related
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5
Q

Antipsychotic PRECAUTIONS

A

elderly
severely ill
diabetic
respiratory insufficiency

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6
Q

Positive symptoms of psychosis examples

A

hallucinations / delusions

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7
Q

1st Gen agents for positive symptoms of Schizo

A

chlorpromazine (Thorazine)
fluphenazine (Prolixin)
haloperidol (Haldol)

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8
Q

Extrapyramidal Side Effects - EPS (b/c of 1st gen meds)

A

dystonia
akathisia
tardive dyskinesia
drug induced parkinsonism

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9
Q

dystonia

A

muscle stiffness

robotic movement

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10
Q

akathisia

A

restlessness
constant movement
unable to sit

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11
Q

tardive dyskinesia

A

abnormal jaw, neck, trapezoid movement

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12
Q

Adverse Drug Reactions of 1st gen meds

A

neuroleptic malignant syndrome (NMS)

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13
Q

NMS symptoms (ICU needed)

A 
severe muscle rigidity
high fever
tachycardia
BP fluctuation
diaphoresis
lowered mental status (coma and stupor)
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14
Q

NMS treatment

A

dantrolene and cooling blankets

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15
Q

Atypical / 2nd Generation meds action

A 
weaker dopamine receptor agonists 
can address (+) or (-) symptoms
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16
Q

2nd Generation CONTRA

A

coma
severely depressed
dementia related psychosis
hx of QT prolongation / cardiac issues

17
Q

2nd Generation PRECAUTIONS

A

elderly
hx seizures
diabetes (metabolic syndrome)
pregnant clients (cross over to fetus)

18
Q

Anticholinergic toxicity effects

A 
dry mouth 
distended bladder
tachycardia
altered mental status
HTN
mydrias
19
Q

Antipsychotic Planning/Implementation

monitor client for what?

A 
anticholinergic effects
PHOTOSENSITIVITY
EKG changes
reduction of seizure threshold
agranulocytosis (clozapine)
metabolic syndrome

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