Antidepressants Flashcards
Med type that:
increases nor epinephrine
SA include anticholinergic effects
Tricyclics
Med type that:
increases serotonin
SA fewer
Favored B/C minimal overdose issues
SSRI’s - Selective Serotonin Reuptake Inhibitors
Med type that:
increases SEROTONIN & NOR EPINEPHRINE
SNRI’s - Serotonin and noradrenaline repuptake inhibitors
Antidepressants ACTION
increases concentration of norepinephrine, serotonin, and/or dopamine
Antidepressants INDICATIONS
dysthymia, anxiety, alcoholism, schizophrenia, depression
Antidepressants CONTRA
acute MI (need 12 lead EKG)
angle-closure glaucoma
CONCOMITANT WITH MAOIs
SSRI medications
Fluoxetine (Prozac)
Sertraline (Zoloft)
Paroxetine (Paxil)
Fluvoxamine (Luvox)
Types of med that causes sleepiness (give @ bedtime)
SSRIs
Adverse reaction to serotinergic medications; can be caused by SSRI/SNRI
Serotonin Syndrome
Serotonin Syndrome S&S
fever, agitation, rigidity, muscle twitching, sweating, cardiac dysrhythmias , seizures (MUST GO TO ICU)
What inactivates norephinephrine, serotonin, and dopamine
MAOI
TCA (Tricyclics) medications
Amitriptyline (Elavil) Clomipramine (anafranil) Doxepine (Sinequan) Imipramine (Tofranil) Trimipramine (Surmontil)
TCA SA
sedation
orthostatic hypotension
anticholinergic
TCA Adverse reaction
cardiotoxicity –> lead to cardiomyopathy
Med used for migraine management, eating disorders, and depression BUT cautiously
TCAs
Amitriptyline (Elavil)
SNRI meds
Bupropion (Wellbutrin) –> anti-smoking med
Venlafaine (Effexor)
Duloxetine (Cymbalta) –> neurolgia
Desvenlafaxine (Pristiq)
Alpha 2 antidepressant
give @ night
for General Anxiety disorder (GAD)
Mirtazapine (Remeron)
Heterocyclic antidepressant
for insomnia properties
Trazadone (desyrel)
Secondary Amine antidepressant
problem w/ pre-existing CVD
hx of seizures
cardiotoxic problems (such as TCAs)
Nortriptyline (Aventyl, Pamelor)
Monitor Client for what antidepressant SA
dry mouth
sedation (take bed @ night)
nausea
Antidepressant PRECAUTIONS
elderly hepatic/renal/cardiac insufficiency psychotic clients clients with BPH hx of seizures
