Antiprotozoans Flashcards
1
Q
indications of metronidazole
A
- trichomoniasis
- amebiasis
- giardiasis
2
Q
AE of metronidazole
A
- disulfiram-like reactions, nausea, peripheral neuropathy
3
Q
CI of metronidazole
A
- pregnancy
4
Q
indications of tinidazole
A
- trichomoniasis
- amebiasis
- giardiasis
5
Q
AE of tinidazole
A
- bitter taste
- acute hypersensitivity reaction (severe), erythema multiforme, SJ syndrome
6
Q
indications of nitazoxanide
A
- diarrhea treatment of crypto in immune competent patients
- diarrhea due to giardia
7
Q
indications of atovaquone
A
- pneuomocystic jiroveci in patients who are intolerant to TMP-SMX
- primary prophylaxis for PCP in HIV pt at high risk of toxo encephalitis
8
Q
indications of pentamidine
A
- treatment and prevention of pneumonia caused by pneumocystic jiroveci
9
Q
AE of pentamidine
A
- cardiac arrythmias
- permanent insulin requiring DM
- pneumonia may still occur despite treatment
10
Q
indications of pyrimethamine
A
- prophylaxis of malaria
- synergistic combo with sulfonamide in treatment of toxo
11
Q
AE of pyrimethamine
A
- must monitor CBC and platelet counts
- discontinue at first sign of rash, report bleeding or bruising
- take with food to minimize vomiting
12
Q
indications of sulfadiazine
A
- toxo
13
Q
AE of sulfadiazine
A
- SJ syndrome, photosensitivity
- supplemental folic acid must be given to avoid folic acid deficiency
14
Q
DOC for trichomonas vaginalis
A
- metronidazole and tinidazole
15
Q
DOC for giardia
A
- metronidazole and tinidazole
