Antiparasitics

Question 1

these antiparasitics are safe and used in most species

Answer 1

tetrahydropyrimidines

Question 2

2 examples of tetrahydropyrimidines

Answer 2

pyrantel

morantel

Question 3

liquid forms of ____ should be shaken before administration

Answer 3

pyrantel

Question 4

be careful when using an organophosphate insecticide with these antiparasitics

Answer 4

tetrahydropyrimidines

Question 5

some of the most commonly used and most effective antiparasitics

Answer 5

benzimidazoles

Question 6

when metabolized, febantel converts to

Answer 6

fenbendazole + oxfenbendazole

Question 7

how to benzimidazoles work?

Answer 7

they interfere with energy metabolism

Question 8

these benzimidazoles can be toxic to the liver

Answer 8

menbendazole

oxibendazole

Question 9

these are grocery store dewormers

Answer 9

piperazines

Question 10

this is the only piperazine found in the vet hospital

Answer 10

diethylcarbamazine citrate (nemacide, filaribits)

Question 11

how do piperazines work?

Answer 11

they paralyze the worms

Question 12

piperazines are only effective against:

Answer 12

ascarids in cats and dogs

Question 13

most common OTC dewormer

Answer 13

piperazines

Question 14

these are mostly used in large animals because there are safer alternatives for small animals

Answer 14

organophosphates

Question 15

with these, observe animals for signs of toxicity

Answer 15

organophosphates

Question 16

most common avermectins used in small animals (2)

Answer 16

• Moxidectin

- Selamectin (Revolution)

Question 17

these are developed from Streptomyces spp.

Answer 17

avermectins

Question 18

how do avermectins work?

Answer 18

they interfere with CNS

Question 19

collies are very sensitive to these

Answer 19

avermectins

Question 20

what is the genetic mutation that can lead to collie toxicity? explain it

Answer 20

MDR-1 they don’t have the transport protein P-glycoprotein that helps remove avermectin molecules out of the CNS

Question 21

older, cheap antiparasitic that has immunostimulant activity

Answer 21

levamisole

Question 22

levamisole is used mostly in ____ animals

Answer 22

large animals