ANTIBIOTICS: penicillins, cephalosporins, aminoclycosides, quinolones Flashcards

1
Q

you can give penicillins on an empty stomach except

A

amoxicillin

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2
Q

this is not absorbed well orally

A

penicillin G

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3
Q

** these are inactivated by organic debris

A

aminoglycosides

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4
Q

penicillin-resistant bacteria secrete this

  • what does it do?
  • what other drugs can be affected by this?
A

beta lactamase enzyme

  • disrupts the structure of penicillin molecule
  • cephalosporins
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4
Q

keep an eye on withdrawal times with this medicine

A

penicillins - a lot of people are allergic

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5
Q

this cephalosporin is a 2 week injectable

A

Convenia (cefovecin)

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6
Q

this cephalosporin is not effective against pseudomonas

A

Convenia (cefovecin)

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8
Q

** these may cause crystal formation in the urine

A

quinolones

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9
Q

this cephalosporin is used for UTIs in cats and skin issues in dogs and cats

A

Convenia (cefovecin)

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10
Q

this cephalosporin used for skin infections is administered SID, which is why it’s sometimes the preferred one

A

Cefpodoxime (Simplicef)

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11
Q

1st generation cephalosporins are effective against

A

G+

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12
Q

2nd generation cephalosporins are effective against

A

G+ and some G-

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12
Q

these are not usually used in food animals because they have long Ass withdrawal times

A

aminoglycosides

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13
Q

if you’re allergic to penicillins, you’re probably also allergic to these:

A

cephalosporins

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13
Q

** these are hydrophillic at physiologic pH

A

aminoglycosides

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14
Q

** these are not well absorbed by the GI tract or uterus

A

aminoglycosides

16
Q

** with these, use caution in animals with renal disease and poor renal perfusion

A

aminoglycosides

17
Q

** these are potentially toxic to kidneys if overdosed

A

cephalosporins

18
Q

** these 2 can cause superinfection in guinea pigs, hamsters, and rabbits (kills G+ bacteria in intestine and leaves G-)

A
  • penicillins

- lincosamides

19
Q

** some of these should not be mixed with penicillin in the same syringe

A

aminoglycosides

20
Q

these are the newest antibiotic group

A

quinolones

21
Q

these are reserved for treatment of more serious infections

A

quinolones

22
Q

** with these, GI absorption is poor in mature ruminants

A

quinolones

24
Q

** these accumulate in the inner ear (cause hearing loss) and kidney (causing toxicity)

A

aminoglycosides

25
Q

** these may cause damage to articular cartilage of growing dogs and horses (although they treat parvo)

A

quinolones

26
Q

these are not recommended for pregnant animals

A

quinolones