ANTIBIOTICS: tetracyclines, sulfonamides, metronidazole, lincosamides, chloramphenicol, florfenicol Flashcards
this is one of the oldest groups of antibiotics
tetracyclines
these are mostly used in large animals
tetracyclines
these products interfere with the absorption of tetracyclines in the GI tract (3)
- dairy products
- antacids
- antidiarrheal products
these are mostly reabsorbed from the intestine
tetracyclines
these cause yellow discoloration of teeth and bones
tetracyclines
these cause retardation of bone growth in the fetus
tetracyclines
don’t use these in combination with penicillins and cephalosporins (2)
- tetracyclines
- chloramphenicol
this is one of the oldest groups of antibiotics used in animals
sulfonamides
what is a potentiated sulfonamide?
sulfonamide + another antibiotic
these are used for UTIs in large animals
sulfonamides
with these, unchanged molecules are excreted in the urine
sulfonamides
with these, bone marrow suppression can occur with prolonged use
sulfonamides
these can cause permanent dry eye (keratoconjunctivitis sicca - KCS) in dogs
sulfonamides
these can cause crystal formation in urine if they’re not drinking enough water
sulfonamides
this is effective against anaerobic bacteria (Clostridium) and some protozoa (Giardia)
metronidazole
this has an anti-inflammatory effect in the GI tract
metronidazole
do not use these with antidiarrheal products
licosamides
this can be toxic to humans, so we need to use gloves
chloramphenicol
don’t use this in food animals
chloramphenicol
this penetrates all tissues including CNS
chloramphenicol
this can cause bone marrow suppression in animals
chloramphenicol
don’t use this in animals with liver disease
chloramphenicol
cats have a decreased ability to metabolize this
chloramphenicol
florfenicol is approved for use in
cattle
this is non-toxic
florfenicol
florfenicol has a __ day withdrawal time
28 day
florfenicol is used in large animal medicine except for
- adult dairy cows
- veal calves
