ANTIBIOTICS: tetracyclines, sulfonamides, metronidazole, lincosamides, chloramphenicol, florfenicol

Question 1

this is one of the oldest groups of antibiotics

Answer 1

tetracyclines

Question 2

these are mostly used in large animals

Answer 2

tetracyclines

Question 3

these products interfere with the absorption of tetracyclines in the GI tract (3)

Answer 3

• dairy products
• antacids
• antidiarrheal products

Question 4

these are mostly reabsorbed from the intestine

Answer 4

tetracyclines

Question 5

these cause yellow discoloration of teeth and bones

Answer 5

tetracyclines

Question 6

these cause retardation of bone growth in the fetus

Answer 6

tetracyclines

Question 7

don’t use these in combination with penicillins and cephalosporins (2)

Answer 7

• tetracyclines

- chloramphenicol

Question 8

this is one of the oldest groups of antibiotics used in animals

Answer 8

sulfonamides

Question 9

what is a potentiated sulfonamide?

Answer 9

sulfonamide + another antibiotic

Question 10

these are used for UTIs in large animals

Answer 10

sulfonamides

Question 11

with these, unchanged molecules are excreted in the urine

Answer 11

sulfonamides

Question 12

with these, bone marrow suppression can occur with prolonged use

Answer 12

sulfonamides

Question 13

these can cause permanent dry eye (keratoconjunctivitis sicca - KCS) in dogs

Answer 13

sulfonamides

Question 14

these can cause crystal formation in urine if they’re not drinking enough water

Answer 14

sulfonamides

Question 15

this is effective against anaerobic bacteria (Clostridium) and some protozoa (Giardia)

Answer 15

metronidazole

Question 16

this has an anti-inflammatory effect in the GI tract

Answer 16

metronidazole

Question 17

do not use these with antidiarrheal products

Answer 17

licosamides

Question 18

this can be toxic to humans, so we need to use gloves

Answer 18

chloramphenicol

Question 19

don’t use this in food animals

Answer 19

chloramphenicol

Question 20

this penetrates all tissues including CNS

Answer 20

chloramphenicol

Question 21

this can cause bone marrow suppression in animals

Answer 21

chloramphenicol

Question 22

don’t use this in animals with liver disease

Answer 22

chloramphenicol

Question 23

cats have a decreased ability to metabolize this

Answer 23

chloramphenicol

Question 24

florfenicol is approved for use in

Answer 24

cattle

Question 25

this is non-toxic

Answer 25

florfenicol

Question 26

florfenicol has a __ day withdrawal time

Answer 26

28 day

Question 27

florfenicol is used in large animal medicine except for

Answer 27

• adult dairy cows

- veal calves