Antineoplastic Flashcards
1
Q
Antineoplastic (chemo): TOXIC
- target
- rate of growth
- goal
A
- abnormal cells composing neoplasm
- same cycle rate as cells of origin
- destroy cells using many methods
2
Q
Noncell specific vs cell cycle specific
A
- noncell effect during resting phase good for slow growing cancers
- cycle specific effect cells that rapidly multiply
3
Q
Alkylating Agents:
- target type
- concern
A
- noncell specific
- bone marrow suppression
4
Q
Antimetabolites:
- target type
- common drugs
- nursing assessment
A
- S phase specific
- capecitabine (xeloda), cladribine
- dehydration possible
5
Q
Antineoplastic Antibiotics:
- Common drugs
- method of action
- target type
- method of admin
A
- bleomyocin, doxyrubicin
- cytotoxic: cellular DNA synthesis
- rapid replicating cells
- IV (long half life)
6
Q
Myotic Inhibitors:
- target type
- common drugs
- method of action
- method of delivery
- adverse effect
A
- M phase
- taxitear, vinblastine, vinchristine
- interfere with division
- IV
- nerve damage potential
7
Q
hormone modulators:
- common drugs
- method of delivery
- adverse effects
A
- zoladex, firmagon, arimidex
- oral
- hypercalcemia, early menopause
8
Q
Cell specific Agents:
- 2 types
- goal
- common drug
A
- protein tyrosine kinase inhibitors, proteasome inhibitors
- inhibit growth of tumor
- velcade: treatment after 2 therapies have been attempted
