Antifungal Agents

Question 1

Systemic Antifungal: Azole
- method of action (cidal/static)
- 2 common drugs
- method of delivery
- adverse reactions
- patient education

Answer 1

• cidal and static
• ketoconazole, anidulafungin
• IV/oral
• decrease libido
• potential effect on oral contraceptive

Question 2

Systemic Antifungal: Echinocandin
- method of action
- common drug

Answer 2

• cidal
• caspofungin

Question 3

Unique Antifungal: Nystatin & Lamisil:
- method of action (specific)

Answer 3

Effects fungal cell wall

Question 4

Topical Antifungals:
- common drugs (brand name included)
- method of action
- used for ______

Answer 4

• clotrimazole (lotrimin/mycelex), miconazole (munistat), terbinafine (lamisil), undecylenic acid (desenex)
• cidal/static: alter permeability
• diaper rash, athletes foot