Antimycobacterials Flashcards
1
Q
challenges of antimycobacterial treatment
A
difficult to kill slow growth lengthy therapy intracellular forms chronic disease
2
Q
why is it important to give multi drug therapy for mycobacterial infection?
A
spontaneous resistance
3
Q
multi drug regimens for treating TB
A
short course–uncomplicated pulmonary TB
disseminated TB
usually use 4 or more drugs
4
Q
why are usually 4 or more drugs used to treat TB?
A
known exposure to drug resistant strains disseminated disease meningitis severe pulmonary disease multidrug resistant TB
5
Q
which are the 3 drugs for TB that are intracellular and extracellular and that are bactericidal
A
isoniazid
rifampin
pyrazinamide
6
Q
how is leprosy treated
A
consult specialists–program in Louisiana