Antimigrañosos Flashcards

1
Q

tx abortivo para migraña

A

AINES, triptanos, ergotamina + cafeina, lasmiditan

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2
Q

mecanismo de accion de triptanos

A

agonistas de 5HT1b/d

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3
Q

farmacos triptanos

A

sumatripan, zolpmitriptan, almotriptan, eletriptan

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4
Q

efectos adversos de triptanos

A

no usar en px con enfer vasculares

sensacion de calor, humedad e hipertension

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5
Q

mecanismo de accion de ditanes

A

agonsita de receptores 5HT1f

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6
Q

efectos adversos

A

solo una dosis por día

somnolencia, mareo, entumecimiento. se recomienda no manejar

evitar el consumo de otros ISRS

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7
Q

farmacos ditanes

A

lesmiditan

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8
Q

indicaciones generales para la ergotamina

A

tratamiento agudo de migraña
cefalea en racimos

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9
Q

mecanismo de accion de ergotamina

A

agonista de receptores 5HT1b/d, DA, alfa adrenoreceptores

+ cafeina –> vasoconstriccion

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10
Q

efectos adversos de la ergotamina

A

nausea, vomito. calambres, insomnio, mialgias
no usar en px con enfer vasculares perifericas

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11
Q

farmacos gepants 2° generacion

A

ubrogepant, rimegepant

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12
Q

indicaciones generales para gepants

A

tratamiento agudo

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13
Q

mecanismo de accion de los gepants

A

antagonista del recoetir de CGRP

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14
Q

efectos adversos de los gepants

A

nausea, cansancio, mucosa oral seca

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15
Q

farmacos mAbs

A

Fremanezumab, Galcanezumab, Eptinezumab (IV) y Erenumab (R)

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16
Q

indicaciones generales para mAbs

A

tratamiento preventivo

17
Q

mecanismo de accion de los mAbs

A

anticuerpo monoclonal contra CGRP o su receptor