Antimicrobials - Tetracyclines

Question 1

Tetracyclines Overview

What are tetracyclines action to stop bacterial growth

inhibit what?

Answer 1

They inhibit protein synthesis and thus growth by binding to the 30S ribosome.

Question 2

Tetracyclines Overview

Uses

what does it treat

Answer 2

acne treatment
mycoplasma pneumonia (walking pneumonia)
H pylori (stomach bug)

Question 3

Tetracycline Overview

Tetracyclines food timing & who do you not give tetra’s to

Answer 3

-chelation (DO NOT take with milk, one hr before or 2 hrs after)
-children or pregnant women

Question 4

Tetracycline Overview

Adverse Effects

Answer 4

-stains teeth/hinders bone growth
-photosensitivity
-hepato/renal toxic
-superinfection like C. diff (a second infection from antibiotics killing off good bacteria as well)

Question 5

What are the three tetracycline drugs?

Answer 5

tetracycline Hcl
demeclocycline
minocycline

Question 6

Specifics

tetra Hcl

need to know

Answer 6

Need to know: NOT given with food

Question 7

Specific

demeclocycline

need to know, SE, taken for

Answer 7

Need to know: NOT given with food
SE: excessive thirst, urination, tiredness (bones/teeth/dairy are not side effects of this one)
Taken for: pts with excessive ADH and so they can’t pee it will stimulate urine flow

Question 8

Specific

minocycline

need to know, SE, taken for

Answer 8

Need to know: TAKE with food
SE: overall ones
Taken for: acne or periodontal disease