Antimicrobials Flashcards
Animal dervied antimicrobials examples
lysozyme
lactoperoxidase system
lactoferrin
plant derived
eugenol and thymol
lysozyme
hydrolytic enzymes which have the ability to cleave bonds in peptidoglycan. They compromise the integrity of cell wall which leads to lysis of bacteria.
sources of lysozyme
naturally present in mammalian milk and avian eggs
lactoperoxidase system
acts as a catalyst oxidising thiocynate ions in the presence of hydrogen peroxide into hypothiocynanous acid.
hypothiocynates react with suphydryl groups to inactivate metabolic enzymes in bacteria
sources of lactoperoxidase
mammalian milk tears and saliva
lactoferrin
component of whey protein. Has the ability to bind to iron and make it unavailable to bacteria. Disrupts microbial cell membrane and interferes with microbial adhesion to host cells
lactoferrin is found?
wherever body needs quick and effective protection against external threat. Kidneys, gallbladder, pancreas
Eugenol examples
clove buds, cinnamon bark and leaves, tulsi leaves, turmeric, pepper, ginger, oregano and thyme.
Thymol examples
thyme, oregano, basil, rosemary,
thymol aka Lamiaceae
family include mint, basil, thyme, oregano, rosemary, and sage
thymol
montoterpene phenol found in essentail oil of lamiaceae family. It is an antioxidant, anti-inflammatory and antimicrobial effects
eugenol
has significant inhibitory effects on numerous kinds of food source MO’s. Inhibits the synthesis of biofilm, chelates iron