antimicrobial susceptibility testing Flashcards
general steps of a dilution
make broth, incubate, read on MIC
what are the diffusion methods
e-test or kirby bauer
what do we measure on the kirby bauer test
zone of inhibition
what is the difference between MIC vs MBC
MIC: min [] that kills
MBC: min [] that inhibits growth
bactericidal drugs. what is the MBC to MIC ratio
MBC to MIC is < or = 4
what are the gold standard things that ideal breakpoints should have
patient species, drug, bacterial species, site.
not all have these
what an MDR organism
phenotypic resistance to more than 3 organisms
what bacti do we know has reliable susceptibility so we probably dont need to test
streps
why do we not use AST for topical therapy
the [] levels are different in intralesion administration of drugs. so we dont trust
G+ cocci in a UTI are likely what
staph pseud
you treat something empirically with enro but the susc test comes back āiā. what do you do
depends on how the dog is responding to treatment. if it is working, stay the course and monitor
recurrant ear infections. what do you want to do
culture and susc test to ensure appropriate treatment is being done
no abx currently on the market can eradicate what?
biofilms
you culture and susc test but its not working. what is one thing to think about
biofilms. especially if intrauterine
