Antihypertensives Flashcards
Main thing to remember =
ABC…D
Normal BP =
140 systolic over 90 diastolic
Causes of hypertension?
- Genetic
- Low birth weight
- Environmental (stress)
- Diabetes
- Drugs (oral contracepive/steroids)
- Cardiovascular or kidney disease
90% of patients have…
Primary hypertension (unknown)
10% of patients have…
Secondary hypertension (known)
Reducing BP means people can avoid…
Strokes, ischaemic heart disease and peripheral vascular disease
What is the BP equation?
BP = CO x TPR
What determines CO?
Venous tone and blood volume
Baroreceptors detect…
Change in pressure
Name the target for antihypertensive drugs (4)…
- Kidney
- Brain
- BV
- Heart
What organ is not a target for anti-hypertensives?
Liver
How do calcium channel blockers work?
Reducing the force of contraction of the heart
Caterpillar blocks the formation of…
Angiotensin II- blocks the ACE enzyme in the lungs which prevents the formation of Angiotensin II