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CVS pharmacology > Antihypertensive Drugs > Flashcards

Antihypertensive Drugs Flashcards

1
Q

Alpha 1 blockers are

A

Prazocin and doxasosin

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2
Q

Combined alpha and beta blocker drug is

A

Labetalol

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3
Q

Adrenergic neuron blockers

A

Alpha methyldopa and reserpine

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4
Q

Vasodilators

A

Hydralazine

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5
Q

Central alpha 2 stimulants

A

Clonidine

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6
Q

Endothelin blockers

A

Bosentan

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7
Q

Dopamine agonist

A

Fenoldopam

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8
Q

ACEIs SH containing drugs …

A

Captopril

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9
Q

ACEIs non SH containing drugs…

A

Ramipril
Lisinopril
Benazepril

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10
Q

ARBs preparations….

A

Losartan
Olmesartan

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11
Q

Competitive inhibition of ANG2 at AT1 receptor

A

ARBs

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12
Q

ACE inhibitors side effects

A

CAPTOPRIL
cough
Angioedema
Proteinuria
Taste changes
Orthostatic hypotension
Pregnancy: teratogenicity
Rashes
Renal failure
Increased k+ due to decreasing of aldosterone
Leucopenia

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13
Q

Cautions of ACE inhibitors

A

Monitor serum of k+ and creatinine

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14
Q

Contraindications of ACE inhibitors

A

Pregnancy
Renal impairment
Dangerous hyperkalemia may occur with potassium sparing diuretics

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15
Q

From Beta blocker drugs and has VD action

A

Carvedilol

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16
Q

Cautions and contraindications of beta blockers

A

Variant angina
Asthma
Avoid abrupt withdrawal

17
Q

Drugs that are both myocardial depressants (inhibi conduction and contraction)

A

Verapamil
Beta blockers

18
Q

Calcium channel blockers

A

Verapamil
Nifedipine
Amlodipine
Diltiazem

19
Q

Relatively cardio selective
-Ve chronotropic and inotropic

A

Verapamil

20
Q

Smooth muscle selective
Potent arterial dilator

A

Nifedipine, amoldipine

21
Q

Intermediate properties

A

Diltiazem

22
Q

Competitive inhibitors of catecholamines

A

Beta blockers

23
Q

Inhibit sympathetic Stimulation of heart

A

Beta blocker

24
Q

Decrease renin release from kidney

A

Beta blockers

25
Q

All of the following are side effects of
Bradycardia
Heart block
Heart failure

A

Beta 1 effect

26
Q

Bronchospasm
Worsening PVD

A

Beta 2 effects

27
Q

AV block
Heart failure
Constipation
Are side effects of …

A

Verapamil and diltiazem

28
Q

Peripheral VD ( flushing, headache)
Reflex tachycardia
Ankle oedema
Are side effects of….

A

Nifedipine and amoldipine

29
Q

Drugs of first choice to treat patients with mild to moderate hypertension

A

Diuretics

30
Q

Preparations of thiazide are …

A

Hydrochlorothiazide
Bendroflumethiazide

31
Q

Drugs that lower BP by renal and extrarenal effects

A

Diuretics

32
Q

Inhibition of NaCl reabsorption is

A

Renal effect

33
Q

Direct VD action on resistance vessels
Vascular response to pressor agents are reduced due to decrease Na content in vascular wall so PG(VD) will increase

A

Extrarenal effects

34
Q

Side effects of diuretics
3hypo
4 hyper

A

Hypokalemia
Hyponatremia
Hypovolemia

Hyperglycemia
Hyperlipidemia
Hyperuricemia
Hypersensitivity

CVS pharmacology (7 decks)

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