Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CVS pharmacology > Anticoagulant > Flashcards

Anticoagulant Flashcards

1
Q

It is a polysaccharide present in mast cells and carry negative charge

A

Heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Has a high molecular weight 30000 Dalton

A

Heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Drug that can’t be taken orally

A

Heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Can’t cross BBB and Placenta

A

Heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Rapid onset and short duration (60 min)

A

Heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Used in emergency

A

Heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Drug that activate antithrombin 3

A

Heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Drugs that inhibit clot factor 10

A

Heparin
Fondaparinux
Rivaroxaban

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

It is an oral inhibitor of factor 10

A

Rivaroxaban

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Antidote of heparin is …

A

Protamine sulfate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

For control of therapy it should be kept 2-3times of it’s normal value

A

Heparin
Warfarin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Bleeding, induced thrombocytopenia, hematoma, osteoporosis and alopecia are adverse effects of which drug ?

A

Heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Has low molecular weight

A

Enoxaparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Has more specific anti factor 10 activity

A

Enoxaparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Has low non specific binding to plasma proteins

A

Enoxaparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

High bioavailability after s.c. injection

A

Enoxaparin

17
Q

Long half life given only once

A

Enoxaparin

18
Q

Thrombocytopenia is less common when the patient take this drug

A

Enoxaparin

19
Q

Low risk of bleeding

A

Enoxaparin

20
Q

Aptt essential lab monitoring

A

Unfractionated heparin

21
Q

Extent inhibitor of.factor 10
Lab monitoring may be unnecessary

A

Enoxaparin

22
Q

Synthesic pentsaccharide drug

A

Fondaparinux

23
Q

It is a selective inhibitor of factor 10

A

Fondaparinux

24
Q

Given by S.C. injection once daily

A

Fondaparinux

25
Q

It is an oral inhibitor of factor 10

A

Rivaroxaban

26
Q

Oral drug that inhibit factor 2

A

Direct thrombin inhibitors
( Dabigatran)

27
Q

Used in treatment of heparin induced thrombocytopenia

A

Direct thrombin inhibitors ( dabigatran)

28
Q

Drug that has good bioavailability (100%)

A

Warfarin

29
Q

It is highly bound to the plasma proteins

A

Warfarin

30
Q

It is biotransformed by hepatic CYP450

A

Warfarin

31
Q

Drug that monitored by Prothrombin time and international normalized ratio

A

Warfarin

32
Q

Antidote of warfarin is

A

Vitamin K1

33
Q

It is an inhibitor of vitamin k .. reductase

A

Warfarin

34
Q

Drug monitored by activated partial thromboplastin time (APTT)

A

Heparin

35
Q

It is an anticoagulant in vivo and vitro

A

Heparin

36
Q

It is an anticoagulant in vivo only

A

Warfarin

37
Q

It is a plasminogen activator and fibrin selective drugs

A

Alteplase

38
Q

The following uses are for which drug
Acute coronary syndrome
Pulmonary embolism
Arterial thrombosis

A

Alteplase ( fibrinolytic drugs)

39
Q

From side effects of fibrinolytic is systemic bleeding
What should we give the patient to antagonize this adverse effect,

A

Antagonized by
Aminocaproic acid and tranexamic

CVS pharmacology (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions