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Pharm Exam 6 > Antihistamines > Flashcards

Antihistamines Flashcards

0
Q

Dimenhydrinate

A

(Dramamine) 1st gen H1 antagonist
Enters CNS- high sedation, anticholinergic-motion sickness
CI: children

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1
Q

Diphenhydramine

A

(Benadryl) 1st gen H1 antagonist
Enters CNS- high sedation, anticholinergic-motion sickness
CI: children

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2
Q

Doxylamine

A

(Unisom)- Sleep aid
1st gen H1 antagonist
Enters CNS- high sedation, anticholinergic-motion sickness
CI: children

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3
Q

Promethazine

A

(Phenergan) 1st gen H1 antagonist
Anti-emetic
Enters CNS- high sedation, anticholinergic-motion sickness
CI: children

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4
Q

Hydroxyzine

A

(Atarax, Vistaril) 1st gen H1 antagonist
For vertigo
Enters CNS- high sedation, anticholinergic-motion sickness
CI: children

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5
Q

Brompheniramine

A

(Bromamine, Dimetane) 1st gen H1 antagonist
moderate sedation
CI: children

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6
Q

Chlorpheniramine (Chlor- Trimeton)

A

1st gen H1 antagonist
moderate sedation
CI: children

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7
Q

Cyclizine (merezine)

A

1st gen H1 antagonist
moderate sedation, motion sickness-anticholinergic
CI: children

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8
Q

Clemastine (Tavist)

A

1st gen H1 antagonist
moderate sedation
CI: children

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9
Q

Meclizine (Bonine)

A

1st gen H1 antagonist
moderate sedation
CI: children

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10
Q

Loratidine

A

(Claritin)
2nd gen H1 antagonist -Non sedating, not anticholinergic
OD: arrhythmias

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11
Q

Desloratadine

A

(Clarinex) - active metabolite
2nd gen H1 antagonist -Non sedating, not anticholinergic
OD: arrhythmias

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12
Q

Certirizine

A

(Zyrtec)
2nd gen H1 antagonist -Non sedating, not anticholinergic
Mild sedation, may also inhibit histamine release from mast cells
Ok in liver disease
OD: arrhythmias

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13
Q

Levocetirizine

A

(Zyxal) - R enantiomer
2nd gen H1 antagonist -Non sedating, not anticholinergic
Ok in liver disease
OD: arrhythmias

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14
Q

Acrivistine

Pseudoephedrine

A

(Semprex)
2nd gen H1 antagonist -Non sedating, not anticholinergic
Ok in liver disease
OD: arrhythmias

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15
Q

Fexofenadine

A

(Allegra)
2nd gen H1 antagonist -Non sedating, not anticholinergic
OD: arrhythmias

16
Q 
Cromolyn Sodium (Intal, Aarane)
Nedcromil (Tilade)
A

Inhibits release of histamine from mast cells
Inhaled
For astma (esp children)

17
Q

Azelastine (Astelin NS, Astepro)

A

Intranasal - Noncompetitive H1 blocker and dec release of histamine
tx: allergic rhinitis

Pharm Exam 6 (8 decks)

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