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Pharmacology > Antihistamines > Flashcards

Antihistamines Flashcards

1
Q

Least sedating 1st generation antihistaminic drug

A

Chlorpheniramine

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2
Q

Most potent H1 blocker

A

Desloratidine

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3
Q

Effect of H1 receptors on bronchi

A

Bronchoconstriction

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4
Q

H1 receptors increase wakefulness in hypothalamus so H1 blockers will be used for the treatment of insomnia or narcolepsy?

A

Insomnia

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5
Q

H2 receptors increase HCL secretion in stomach so H2 blockers will be used for the treatment of?

A

Peptic ulcer disease ( as it will reduce HCl secretion)

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6
Q

Between 1st and 2nd generation H1 blockers which ones are more sedating?

A

1st generation H1 blockers

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7
Q

Examples of 1st gen H1 blockers

A

Promethazine
Diphenhydramine
Dimenhydrinate
Doxylamine
Chlorpheniramine
Hydroxyzine
Meclizine
Cyproheptadine
Doxepin

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8
Q

Examples of 2nd generation H1 blockers

A

Cetrizine
Levocetrizine
Loratidine
Desloratidine
Terfenadine
Fexofenadine
Rupatidine

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Pharmacology (9 decks)

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