Antigens, Antibodies and Complement System Flashcards
target of antibody and T cells
antigen
what part does an antibody bind to on an antigen
epitope
what does a T cell bind to on an antigen
a peptide that is a fragment of an antigen
what “present” antigens for T cells to see
histocompatibility complex proteins
found on the surface of most cells in body, inform killer T cells whats going on INSIDE other cells
Class I histocompatibility complex proteins
made by antigen presenting cells, informs helper T cells problems exist OUTSIDE of cells
Class II histocompatibility complex proteins
doesn’t kill anything, however it plants the “kiss of death” on an invader
TAG IT
antibody
prepare to “eat”
opsonization
can dock on a virus that is still outside cell and tag it to die
neutralizing antibodies
20 different proteins (made by the liver) working together to destroy invaders/signal immune system players “attack” is on
complement system
what are the functions of complement sysytem
builds membrane attack complexes
- multi-functional cells- enhance fix of phag cells
- alert other cells being attacked
- VERY FAST SYSTEM
complement classical pathway
depends on antibodies for activation
complement alternative pathway
antibody independent
man loves carb pizza
lectin activation path
mannose binds lectin, lectin binds carb molecule, carb molecule on pathogens
triggers inflammation
chemotactically attracts phagocytes to infection
promotes attachment antigen, 2nd signal for b-lymphocytes
causes lysis of gram negative bacteria and foreign epitopes
harmful immune complexes removed from body
lectin activation path
