Antigen Presentation - Week 4 PBL

Question 1

List three antigen presenting cells?

Answer 1

Macrophages
B cells
Dendritic cells

Question 2

Purpose of antigen presenting cells?

Answer 2

To inform adaptive response of the immune system

Question 3

How does antigen presentation work?

Answer 3

1) antigen is taken up by phagocytosis and processsed into vesicles
2) MHC class II peptide-antigen on APC recognised by CD4+ cell
3) CD4+ cell activates macrophages and kills phagocytosis oaathogen
4) B cell acts as an APC
5) MHC class II peptide-antigen activates CD4+ cell to secrete cytokines and helps B cell to secrete Ig
6) Antibody binds to extracellular antigen