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Chapter 17: Raskin & Meyer > Antigen Markers, Sources, Tissue Controls, & Uses for Antibodies Used in Dogs/Cats > Flashcards

Antigen Markers, Sources, Tissue Controls, & Uses for Antibodies Used in Dogs/Cats Flashcards

1
Q

What is the tissue control & use for the actin muscle antigen in dogs?

A
  • skeletal muscle/heart

- muscle neoplasms

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2
Q

What is the tissue control & use for the actin sarcomeric antigen in dogs?

A
  • skeletal muscle/heart

- striated muscle tumors

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3
Q

What is the tissue control & use for the actin smooth muscle antigen in dogs?

A
  • stomach/intestine

- smooth muscle tumors

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4
Q

What is the tissue control & use for the adenovirus antigen in dogs?

A
  • infected tissue

- infection

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5
Q

What is the tissue control & use for the amylin (IAPP) antigen in cats & dogs?

A
  • pancreas

- pancreatic islet amyloid

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6
Q

What is the tissue control & use for the Bcl-2 oncoprotein antigen in cats?

A
  • lymphoid tissue

- lymphoid tumors

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7
Q

What is the tissue control & use for the B-lymphocyte antigen (BLA.36) in cats & dogs?

A
  • lymph node, spleen

- B-cell, histiocytic tumors

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8
Q

What is the tissue control & use for the CD1c (ICC) antigen in dogs?

A
  • lymphoid tissue

- dendritic cell tumors

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9
Q

What is the tissue control & use for the CD3 (ICC) antigen in dogs?

A
  • lymph node, spleen

- T-cell lymphoma

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10
Q

What is the tissue control & use for the CD3 epsilon (IHC) antigen in cats & dogs?

A
  • lymph node, spleen

- T-cell lymphoma

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11
Q

What is the tissue control & use for the CD10 (CALLA antigen) in dogs?

A
  • kidney

- renal, stromal tumors

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12
Q

What is the tissue control & use for the CD11d (IHC) antigen in dogs?

A
  • spleen

- lymphoid, histiocytic tumors

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13
Q

What is the tissue control & use for the CD11d (ICC) antigen in cats & dogs?

A
  • spleen

- lymphoid, histiocytic tumors

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14
Q

What is the tissue control & use for the CD18 antigen in cats?

A
  • spleen

- leukocytic tumors

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15
Q

What is the tissue control & use for the CD18 antigen in dogs?

A
  • spleen, lymph node

- leukocytic tumors

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16
Q

What is the tissue control & use for the CD20 antigen in cats & dogs?

A
  • spleen, lymph node

- B-cell tumors

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17
Q

What is the tissue control & use for the CD31 antigen in dogs?

A
  • skin, other

- vascular endothelial & megakaryocytic tumors

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18
Q

What is the tissue control & use for the CD45 antigen in dogs?

A
  • spleen, lymph node

- leukocytic tumors

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19
Q

What is the tissue control & use for the CD45RA antigen in dogs?

A
  • lymphoid tissue

- lymphoid tumors

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20
Q

What is the tissue control & use for the CD79a antigen in cats & dogs?

A
  • lymph node, spleen

- B-cell lymphoma

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21
Q

What is the tissue control & use for the CD117 (c-Kit protein) antigen in dogs?

A
  • mast cell tumor

- mast cell tumor

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22
Q

What is the tissue control & use for the calcitonin antigen in cats & dogs?

A
  • thyroid

- C-cell tumors

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23
Q

What is the tissue control & use for the calponin antigen in dogs?

A
  • small intestine, stomach

- smooth muscle & myoepithelial tumors

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24
Q

What is the tissue control & use for the calretinin antigen in cats & dogs?

A
  • kidney

- renal tubules, nerve tissue, adrenocortical tumors, mesothelioma

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25
Q

What is the tissue control & use for the canine distemper virus antigen in dogs?

A
  • infected tissue

- infection

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26
Q

What is the tissue control & use for the carcinoembryonic antigen in dogs?

A
  • intestine

- epithelial tumors

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27
Q

What is the tissue control & use for the caspase-3 antigen in dogs?

A
  • lymph node

- apoptotic cells

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28
Q

What is the tissue control & use for the chromogranins A & B antigen in dogs?

A
  • pancreas

- neuroendocrine tumor

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29
Q

What is the tissue control & use for the coronavirus antigen in cats & dogs?

A
  • infected tissue

- infection

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30
Q

What is the tissue control & use for the COX-1 antigen in dogs?

A
  • normal urinary bladder

- normal urothelium, endothelium

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31
Q

What is the tissue control & use for the COX-2 antigen in cats & dogs?

A
  • transitional cell carcinoma

- carcinomas

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32
Q

What is the tissue control & use for the cytokeratin 5 antigen in dogs?

A
  • mammary gland, skin

- myoepithelium, basal cells

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33
Q

What is the tissue control & use for the cytokeratin 7 antigen in dogs?

A
  • skin, urinary bladder

- glandular epithelium

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34
Q

What is the tissue control & use for the cytokeratins 8/18 antigen in dogs?

A
  • liver, stomach

- glandular epithelium

35
Q

What is the tissue control & use for the cytokeratins AE1-AE3 antigen in cats & dogs?

A
  • skin

- general epithelium marker

36
Q

What is the tissue control & use for the cytokeratins Pan antigen in dogs?

A
  • glandular/squamous epithelium

- general epithelium marker

37
Q

What is the tissue control & use for the cytokeratins HMW antigen in dogs?

A
  • skin

- squamous epithelium, mesothelium, hepatocytes

38
Q

What is the tissue control & use for the desmin antigen in dogs?

A
  • skin, stomach, intestine

- muscle tumors

39
Q

What is the tissue control & use for the E-cadherin antigen in dogs?

A
  • skin

- Langerhan’s cells, epithelium, histiocytoma, meningiomas

40
Q

What is the tissue control & use for the estrogen receptor alpha in cats & dogs?

A
  • uterus

- estrogen receptor tumors

41
Q

What is the tissue control & use for the factor VIII-related antigen in dogs?

A
  • skin, other

- vascular endothelial & megakaryocytic tumors

42
Q

What is the tissue control & use for the feline calcivirus antigen in cats?

A
  • infected tissue

- infection

43
Q

What is the tissue control & use for the feline herpesvirus 1 antigen in cats?

A
  • infected tissue

- infection

44
Q

What is the tissue control & use for the feline leukemia virus antigen in cats?

A
  • infected tissue

- infection

45
Q

What is the tissue control & use for the glial fibrillary acidic protein antigen in dogs?

A
  • brain

- neural (glial) tumors

46
Q

What is the tissue control & use for the glucagon antigen in cats & dogs?

A
  • pancreas

- glucagon-producing tumors

47
Q

What is the tissue control & use for the Glut-1 antigen in dogs?

A
  • peripheral nerve

- peripheral nerves, stromal cells, kidney

48
Q

What is the tissue control & use for the hepatocyte marker-1 (Hep Par 1) antigen in dogs?

A
  • liver

- hepatocellular tumors

49
Q

What is the tissue control & use for the Ig kappa chains antigen in dogs?

A
  • lymph node

- plasmacytomas

50
Q

What is the tissue control & use for the Ig lambda chains antigen in dogs?

A
  • lymph node

- plasmacytomas

51
Q

What is the tissue control & use for the immunoglobulin M antigen in cats & dogs?

A
  • lymph node

- lymphoid tumors

52
Q

What is the tissue control & use for the inhibin-alpha antigen in dogs?

A
  • testicle, Sertoli cell tumor

- sex cord - stromal & adrenal cortical tumors

53
Q

What is the tissue control & use for the insulin antigen in dogs?

A
  • pancreas

- insulin-producing tumors

54
Q

What is the tissue control & use for the Ki-67 antigen in dogs?

A
  • lymphoma

- cell proliferation marker

55
Q

What is the tissue control & use for the laminin antigen marker in cats & dogs?

A
  • skin/kidney

- perivascular wall tumors & basement membrane

56
Q

What is the tissue control & use for the Leptospira antigen in dogs?

A
  • infected tissue

- infection

57
Q

What is the tissue control & use for the lysozyme antigen in cats & dogs?

A
  • liver, spleen

- histiocytes

58
Q

What is the tissue control & use for the Melan A antigen in cats & dogs?

A
  • melanoma

- melanomas, steroid-producing tumors

59
Q

What is the tissue control & use for the MHC II antigen in dogs?

A
  • histioyctoma, lymph node

- antigen presenting cells, lymphocytes

60
Q

What is the tissue control & use for the microphthalmia transcription factor antigen in dogs?

A
  • melanoma

- melanomas

61
Q

What is the tissue control & use for the MUM 1 protein antigen in dogs?

A
  • plasmacytoma

- plasmacytomas, myelomas, some B-cell tumors

62
Q

What is the tissue control & use for the myeloid/histiocytic antigen in dogs?

A
  • spleen, liver

- macrophages, myeloid cells

63
Q

What is the tissue control & use for the myoglobin antigen in dogs?

A
  • skeletal muscle, heart

- skeletal muscle tumors

64
Q

What is the tissue control & use for the Neospora caninum antigen in dogs?

A
  • infected tissue

- infection

65
Q

What is the tissue control & use for the nerve growth factor receptor antigen in dogs?

A
  • nerve

- nerves

66
Q

What is the tissue control & use for the neurofilament-2 antigen in dogs?

A
  • brain

- neuron neurofilaments

67
Q

What is the tissue control & use for the neuron specific enolase antigen in dogs?

A
  • pancreas

- neuroendocrine marker

68
Q

What is the tissue control & use for the OCT3/4 antigen in dogs?

A
  • mast cell tumor

- germ cell & mast cell tumors

69
Q

What is the tissue control & use for the p63 antigen in dogs?

A
  • skin, mammary gland

- myoepithelium, basal cells

70
Q

What is the tissue control & use for the papilloma virus in dogs?

A
  • infected tissue

- infection

71
Q

What is the tissue control & use for the parathyroid hormone antigen in dogs?

A
  • parathyroid

- normal & neoplastic parathryoid

72
Q

What is the tissue control & use for the parvovirus antigen in dogs?

A
  • infected tissue

- infection

73
Q

What is the tissue control & use for the progesterone receptor antigen in dogs?

A
  • uterus

- progesterone receptor tumors

74
Q

What is the tissue control & use for the proliferating cell nuclear antigen in dogs?

A
  • lymphoma, lymph node

- proliferation marker

75
Q

What is the tissue control & use for the Protein Gene Product 9.5 antigen in cats & dogs?

A
  • adrenal gland

- neuroendocrine marker

76
Q

What is the tissue control & use for the S-100 protein antigen in cats & dogs?

A
  • nerve, brain

- neural marker, neuroendocrine tumors

77
Q

What is the tissue control & use for the somatostatin antigen in dogs?

A
  • pancreas

- pancreatic islet tumors, some carcinoids

78
Q

What is the tissue control & use for the synaptophysin antigen in dogs?

A
  • pancreas

- neuroendocrine marker

79
Q

What is the tissue control & use for the thyroglobulin antigen in cats & dogs?

A
  • thyroid

- thyroglobulin-producing tumors

80
Q

What is the tissue control & use for the thyroid transcription factor-1 antigen in dogs?

A
  • lung, thyroid

- lung & thyroid neoplasms

81
Q

What is the tissue control & use for the Toxoplasma gondii antigeni in cats?

A
  • infected tissue

- infection

82
Q

What is the tissue control & use for the tryptase antigen in dogs?

A
  • mast cell tumor

- mast cell tumors

83
Q

What is the tissue control & use for the uroplakin III antigen in dogs?

A
  • urinary bladder

- urothelial neoplasms

84
Q

What is the tissue control & use for the vimentin antigen in dogs?

A
  • skin, stomach

- mesenchymal tumor marker

Chapter 17: Raskin & Meyer (6 decks)

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