Ancillary Diagnostic Testing in Lymphoma and Leukemia

Question 1

You have a confirmed lymphoma patient, but want phenotypic information. What test and site do you use?

Answer 1

flow cytometry, IHC, ICC; lymph node

Question 2

You have a suspected lymphoma patient with suspect cytology/histology. What test and site do you use to confirm?

Answer 2

PARR; lymph node or involved organ

Question 3

You have a patient with a lymphocytosis or leukemia. What test and site do you use for more information?

Answer 3

flow cytometry, ICC; peripheral blood

Question 4

You have a patient with rare, suspicious cells in the peripheral blood with no lymphocytosis. What test and site do you use for more information?

Answer 4

PARR; peripheral blood

Question 5

You have a patient with splenomegaly. What test and site do you use for more information?

Answer 5

PARR; spleen

Question 6

You have a patient with a mass or aspirate containing cells of unclear origin. What test and site do you use for more information?

Answer 6

IHC, ICC, flow cytometry if cellular and PARR if not

Question 7

You have a patient with a lymphocyte rich effusion. What test and site do you use for more information?

Answer 7

flow cytometry, IHC, ICC; effusion fluid