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Drug List 1-5 > ANTIFUNGAL > Flashcards

ANTIFUNGAL Flashcards

1
Q

Antifungals/ Polyenes

A

Nystatin

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2
Q

Nystatin INDICATION

A

skin and GI Candida infections

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3
Q

Nystatin ROA

A

PO, topical

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4
Q

Nystatin MOA

A

Binds to ergosterol to change the cell membrane; pores form that allow ions to flow out which leads to cell death

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5
Q

Nystatin AE

A

PO: N/V/D, cramps Topical: rash, urticaria

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6
Q

Antifungals/ Azoles: 2 DRUGS

A

Fluconazole

Ketoconazole

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7
Q

Antifungals/ Azoles INDICATION

A

broad spectrum; systemic infection to mild genital yeast infections

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8
Q

Antifungals/ Azoles ROA

A

Fluconazole: PO, IV
Ketoconazole: PO

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9
Q

Antifungals/ Azoles MOA

A

inhibits synthesis of ergosterol in the cell membrane

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10
Q

Antifungals/ Azoles AE

A

N/V, photophobia, cardiac arrythmia, menstrual irregularities, hepatotoxicity

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11
Q

Antifungals/ Azoles PK/PD

A

often has drug interactions due to impact on CYP enzymes, especially ketoconazole

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Drug List 1-5 (8 decks)

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