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Drug List 1-5 > ANTIBIOTICS > Flashcards

ANTIBIOTICS Flashcards

1
Q

Antibiotics/ Penecillins

A

Amoxicillin
Amoxicillin/Clavulanate (Augmentin)
Piperacillin/Tazobactam (Zosyn)

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2
Q

Antibiotics/ Penecillins INDICATION

A

Common for broad coverage of Gram- and Gram+

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3
Q

Antibiotics/ Penecillins ROA

A

PO, IV

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4
Q

Antibiotics/ Penecillins MOA

A

inhibit cell wall synthesis

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5
Q

Antibiotics/ Penecillins AE

A

GI, hypersensitivity/allergies

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6
Q

Antibiotics/ Cephalosporins

A

Cephalexin (Keflex)

Cephtriaxone (Rocephin)

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7
Q

Antibiotics/ Cephalosporins INDICATION

A

Cephalexin: surgical prophylaxis, SSTIs

Cephtriaxone: surgical prophylaxis, community-acquired pneumonia, meningitis, gonorrhea, severe Lyme disease

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8
Q

Antibiotics/ Cephalosporins MOA

A

inhibit cell wall synthesis

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9
Q

Antibiotics/ Cephalosporins AE

A

GI, hypersensitivity

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10
Q

Antibiotics/ Cephalosporins PK/PD

A

Caution for severe and immediate PCN allergy due to cross-reactivity

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11
Q

Antibiotics/ Cephalosporins OTHER

A

Cephalexin: 1st generation
Cephtriaxone: 3rd generation

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12
Q

Antibiotics/ Glycopeptides

A

Vancomysin

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13
Q

Vancomysin INDICATION

A

MRSA, C. diff, increasing resistance (VRE)

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14
Q

Vancomysin ROA

A

IV, PO for C. diff

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15
Q

Vancomysin MOA

A

inhibit cell wall synthesis

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16
Q

Vancomysin AE

A

Hypotension, red man syndrome, nephrotoxicity

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17
Q

Antibiotics/ Aminoglycosides

A

Gentamicin

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18
Q

Gentamicin INDICATION

A

Gram- bacilli, staph, myobacteria

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19
Q

Gentamicin ROA

A

IV, PO, inhaled, topical, ophthalmic, intraventricular (CSF shunt)

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20
Q

Gentamicin MOA

A

inhibit bacterial protein synthesis

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21
Q

Gentamicin AE

A

Ototoxicity, nephrotoxicity

22
Q

Antibiotics/ macrolides

A

Azithromycin (Z-pack)

23
Q

Azithromycin (Z-pack) INDICATION

A

Some Gram+ and Gram-, pneumonia, respiratory infections, CAP

24
Q

Azithromycin (Z-pack) ROA

A

PO, IV, ophthalmic

25
Q

Azithromycin (Z-pack) MOA

A

inhibit bacterial protein synthesis

26
Q

Azithromycin (Z-pack) AE

A

Common: N/V/D QT prolongation, CYP450 inhibitors (DDI)

27
Q

Antibiotics/ Tetracycline

A

Doxycycline

28
Q

Doxycycline INDICATION

A

Broad coverage of Gram+ and Gram- and atypicals PNA, SSTIs, Lyme, bite wounds, STIs

29
Q

Doxycycline ROA

A

PO, IV

30
Q

Doxycycline MOA

A

inhibit bacterial protein synthesis

31
Q

Doxycycline AE

A

Typically tolerated well, yellowing of teeth GI, photosensitivity

32
Q

Doxycycline OTHER

A

Contraindicated in pregnant & breast-feeding women and children under 8

33
Q

Antibiotics/ Lincosamide

A

Clindamycin

34
Q

Clindamycin INDICATION

A

Gram+, SSTIs, anaerobic intra-abdominal infections, acne

35
Q

Clindamycin ROA

A

topical for acne

36
Q

Clindamycin AE

A

GI (D), can cause C. diff

37
Q

Antibiotics/ Fluoroquinolines

A

Ciprofloxacin

Levofloxacin (Levaquin)

38
Q

Fluoroquinolines INDICATION

A

Gram-, pneumonia, chronic bronhitis, CAP, STIs, anthrax, plague, prostatitis, bite wounds, TB, diabetic foot ulcers, SSTIs

39
Q

Fluoroquinolines ROA

A

PO, IV, ophthalmic, otic

40
Q

Fluoroquinolines MOA

A

inhibit bacterial DNA synthesis or break down DNA strands

41
Q

Fluoroquinolines AE

A

Generally tolerated well. GI, phototoxicity RARE: tendon rupture, significant hypoglycemia

42
Q

Fluoroquinolines OTHER

A

Boxed Warning s do not apply to opthalmic routes reserved for serious systemic infections due to risks

43
Q

Antibiotics/ Nitroimidazole

A

Metronidazole (Flagyl)

44
Q

Nitroimidazole INDICATION

A

Anaerobes, C. diff, bacterial vaginosis, Chron’s disease, pelvic inflammatory disease, GI infections

45
Q

Nitroimidazole ROA

A

PO, IV

46
Q

Nitroimidazole MOA

A

inhibit bacterial DNA synthesis or break down DNA strands

47
Q

Nitroimidazole AE

A

HA, vaginitis, nausea, metallic taste Less Common: peripheral neuropathy, vomit with alcohol

48
Q

Antibiotics/ Antifolates

A

Sulfamethoxazole/Trimethoprim (Bactrim)

49
Q

Antifolates INDICATION

A

Broad coverage of Gram+ and Gram-, UTIs, infectious diarrhea, alternative MRSA treatment

50
Q

Antifolates MOA

A

inhibit bacterial DNA synthesis or break down DNA strands

51
Q

Antifolates AE

A

can cause allergy Rare but serious derm reactions: Toxic Epidermal Necrolysis, Stevens-Johnson syndrome

Drug List 1-5 (8 decks)

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