Antifungal Flashcards

1
Q

Amphotericin and nystatin are

A

Polyenes

Create pore in fungal wall

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2
Q

Drugs ending in azole are

A

Triazoles

Inhibit ergosterol

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3
Q

Caspofunigan, micafunigan are

A

Echinocandinan

Inhibit cell wall glucan

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4
Q

Flucytosine is

A

Pyrimidine

Inhibit fungal RNA and protein

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5
Q

Main classes of antifungals

A

Polyene- creates pore in membrane

Triazoles- inhibits synth of ergosterol

Echinocandins- inhibits glucan, fungal wall

Pyrimidines- interferes with fungal RNA and protein synth

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