Antifungal Flashcards
1
Q
Amphotericin and nystatin are
A
Polyenes
Create pore in fungal wall
2
Q
Drugs ending in azole are
A
Triazoles
Inhibit ergosterol
3
Q
Caspofunigan, micafunigan are
A
Echinocandinan
Inhibit cell wall glucan
4
Q
Flucytosine is
A
Pyrimidine
Inhibit fungal RNA and protein
5
Q
Main classes of antifungals
A
Polyene- creates pore in membrane
Triazoles- inhibits synth of ergosterol
Echinocandins- inhibits glucan, fungal wall
Pyrimidines- interferes with fungal RNA and protein synth