Antiemetics Flashcards
Name an anticholinergic antiemetic
Hyoscine
What dose and route of administration is used for hyoscine?
0.2-0.4 mg
SC or IM
6 hourly
What are the side effects of hyoscine?
Dry mouth
Blurred vision
Dizziness
Confusion
Name an antihistamine antiemetic
Cyclizine
What dose and route of cyclizine is used?
50 mg
PO/IM/IV
8 hourly
Name three dopamine antagonist antiemetics
Prochlorperazine
Metoclopramide
Domperidone
Droperidol
What dose and route is used for prochlorperazine?
12.5 mg IM
3 mg buccal
6 hourly
What dose and route is used for metoclopramide?
10mg
IM/IV
8 hourly
What dose and route is used for droperidol?
0.5 - 1.25 IV
2.5-5 mg PO
8 hourly
What dose and route is used for domperidone?
10 mg PO
Name 2 5HT3 antagonist antiemetics
Ondansetron
Granisetron
Tropisetron
Palonsetron
What are the common side effects of D2 antagonists?
Extrapyramidal
Sedation
What is the dose and route of ondansetron.
1-8 mg
PO IM IV
8 hourly
What are the common side effects of 5HT3 antagonists?
Hypersensitivity
Headache
Transient elevation in LFTs
What is the antiemetic dose of dexamethasone?
2-8 mg
IV
Single prophylactic dose