Antiemetics Flashcards

1
Q

Name an anticholinergic antiemetic

A

Hyoscine

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2
Q

What dose and route of administration is used for hyoscine?

A

0.2-0.4 mg
SC or IM
6 hourly

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3
Q

What are the side effects of hyoscine?

A

Dry mouth
Blurred vision
Dizziness
Confusion

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4
Q

Name an antihistamine antiemetic

A

Cyclizine

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5
Q

What dose and route of cyclizine is used?

A

50 mg
PO/IM/IV
8 hourly

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6
Q

Name three dopamine antagonist antiemetics

A

Prochlorperazine
Metoclopramide
Domperidone
Droperidol

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7
Q

What dose and route is used for prochlorperazine?

A

12.5 mg IM
3 mg buccal
6 hourly

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8
Q

What dose and route is used for metoclopramide?

A

10mg
IM/IV
8 hourly

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9
Q

What dose and route is used for droperidol?

A

0.5 - 1.25 IV
2.5-5 mg PO
8 hourly

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10
Q

What dose and route is used for domperidone?

A

10 mg PO

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11
Q

Name 2 5HT3 antagonist antiemetics

A

Ondansetron
Granisetron
Tropisetron
Palonsetron

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12
Q

What are the common side effects of D2 antagonists?

A

Extrapyramidal

Sedation

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13
Q

What is the dose and route of ondansetron.

A

1-8 mg
PO IM IV
8 hourly

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14
Q

What are the common side effects of 5HT3 antagonists?

A

Hypersensitivity
Headache
Transient elevation in LFTs

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15
Q

What is the antiemetic dose of dexamethasone?

A

2-8 mg
IV
Single prophylactic dose

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16
Q

Patient factors for PONV

A

Female
Non-smoker
Past episodes
Motion sickness

17
Q

Surgical factors for ponv

A
Laparoscopic 
Strabismus
Middle ear 
ENT
Gynae
18
Q

Anaesthetic factors for ponv

A

Opioids
Volatile gasses
Nitrous oxide
GA vs RA