antidotes(cyanide kits) Flashcards

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1
Q

Class

amyl nitrate

A

Antidote, cyanide poisoning adjunct

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2
Q

description

amyl nitrate

A

converts hemoglobin to methemogolobin, which reacts with cyanide and chemically binds with it, preventing any toxic effects

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3
Q

indications

amyl nitrate

A

cyanide poisoning

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4
Q

contraindications

amyl nitrate

A

none in emergency setting

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5
Q

precautions

amyl nitrate

A

headache, dizziness, weakness, increased ICP, shortness of breath, orthostatic hypotension, tachycardia

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6
Q

dosage/route

amyl nitrate

A

1-2 ampules crushed and inhaled for 30 seconds of each minute until sodium nitrate is prepared of administered for 30-60 seconds every 5 minutes untill patient is conscious

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7
Q
class
sodium nitrate
A

antidote, cyanide poisoning adjunct

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8
Q

description

sodium nitrate

A

reacts with hemoglobin to form methemoglobin, which reacts with cyanide and chemically binds with it to prevent toxic effect

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9
Q

indications

sodium nitrate

A

cyanide poisoning

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10
Q

contraindications

sodium nitrate

A

none in emergency settings

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11
Q

precautions/side effects

sodium nitrate

A

hypotension, tachycardia, fainting, nausea, omiting

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12
Q

dosage/route

sodium nitrate

A

300mg (10mL of a 3% solutions) slow IV push over 5 minutes or dillute 300 mg in 100 mL of saline and infuse slowly

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13
Q
class
sodium thiosulfate
A

cyanide antidote

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14
Q

description

sodium thiosulfate

A

converts cyanide to less toxic thiocyanate, which is then excreted in the urine

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15
Q

indications

sodium thiosulfate

A

cyanide poisioning

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16
Q

dosage/route

sodium thiosulfate

A

12.5g(50mL of 25% solution) IV/IO slow push over 10 min

17
Q

pedi dosage/route

sodium thiosulfate

A

400mg/kg (1.65 mL/kg of a 25% solution) IV/IO slow push