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Pharm Exam 2 > Antidiabetics Class > Flashcards

Antidiabetics Class Flashcards

1
Q

chlorpropamide

A

first gen sulfonylurea

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2
Q

chlorpropamide

A

first gen sulfonylureas

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3
Q

tolazamide

A

first gen sulfonylureas

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4
Q

tolbutamide

A

first gen sulfonylureas

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5
Q

glyburide

A

2nd gen sulfonylureas

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6
Q

glimepiride

A

2nd gen sulfonylureas

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7
Q

glipizide

A

2nd gen sulfonylureas

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8
Q

sulfonylureas

A

stimulate release of insulin from pancreas, increase cell sensitivity to insulin

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9
Q

do sulfonylureas cause hypoglycemia

A

yes

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10
Q

metformin

A

buganide

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11
Q

Buganide

A

decrease hepatic production of glucose, decrease intestinal reabsorption of glucose, increase cell uptake of glucose

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12
Q

do buganides cause hypoglycemia

A

no

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13
Q

repaglinide

A

meglitinide

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14
Q

nateglinide

A

meglitinide

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15
Q

Meglitinide

A

stimulate release of insulin from pancreas

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16
Q

do meglitinides cause hypoglycemia

A

yes

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17
Q

rosiglintazone

A

thiazolidinedione

18
Q

pioglintazone

A

thiazolidinedione

19
Q

Thiazolidinediones

A

increase cell sensivity to insulin and decrease hepatic production of glucose, take 3-4mo

20
Q

albiglutide

A

incretin mimetic agonist

21
Q

dulaglutide

A

incretin mimetic agonist

22
Q

exeratide

A

incretin mimetic agonist

23
Q

liraglutide

A

incretin mimetic agonist

24
Q

lixisenatide

A

incretin mimetic agonist

25
Q

incretin mimetic agonist

A

activate GLP-1, increase insulin secretion, decrease glucagon secretion, delay gastric emptying, slow glucose aborption, increase statiety

26
Q

alogliptin

A

incretin enhancer

27
Q

linagliptin

A

incretin enhancer

28
Q

saxagliptin

A

incretin enhancer

29
Q

sitagliptin

A

incretin enhancer

30
Q

incretin enchancer

A

prevent breakdown of incretin/GLP-1, increase insulin secretion, decrease glucagon secretion, delay gastric emptying, slow glucose absortption, increase statiety

31
Q

do incretin mimetic agonists cause hypoglycemia

A

no

32
Q

do incretin enhancers cause hypoglycemia

A

no

33
Q

acarbose

A

alpha glucosidase inhibitor

34
Q

miglitol

A

alpha glucosidase inhibitor

35
Q

do alpha glucosidase inhibitors cause hypoglycemia

A

no

36
Q

bromocriptine

A

dopamine receptor antagonist

37
Q

does bromocriptine cause hypoglycemia

A

no

38
Q

canagliflozin

A

sodium-glucose cotransporter inhibitor

39
Q

dapagliflozin

A

sodium-glucose cotransporter inhibitor

40
Q

empagliflozin

A

sodium-glucose cotransporter inhibitor

41
Q

sodium-glucose cotransporter inhibitor MoA

A

inhibit SGCI in kidney, lose glucose in urine

Pharm Exam 2 (9 decks)

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