antidepressants Flashcards

1
Q

Imiprazine

A

Class: TCA (tertiary amine)
Mechanism: NE/5-HT uptake
Side Effects: arrhythmias, av block, orthostatic hypotension

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2
Q

Desipramine

A

Class: TCA (secondary amine)
Mechanism: NE uptake
Side Effects: arrhythmias, av block, orthostatic intolerance

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3
Q

Fluoxetine

A

Class: SSRI
Mechanism: 5-HT uptake
Side Effects: Nausea, vomiting, sexual dysfunction, asthenia

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4
Q

venlafaxine

A

Class: SNRI
Mechanism: low dose NE uptake, high dose NE/5HT uptake
Side Effects: nausea vomiting, sexual dysfunction, asthenia

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5
Q

Phenelzine

A

Class: MAOI
Mechanism: irreversible MAO inhibition
Side Effects: hepatotoxicity, CNS, orthostatic hypotension, Cheese Rxn hypertensive crisis (tyramine)

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6
Q

Mirtazapine

A

Class: not classified
Mechanism: alpha-2 adrenoceptor blockade
Side Effects: weight gain

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