Anticonvulsant CYP Flashcards

1
Q

Which anticonvulsants are 3A4 substrates?

A
Clobazem
Carbazepime
Clonazepam
Perampanel
Oxcarbazapine
Ethosuximide
Topiramate
Tiagabine
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2
Q

Which anticonvulsants are 2C9 substrates?

A

Phenobarbital

Phenytoin

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3
Q

Which anticonvulsants are 2C19 substrates?

A

Phenytoin
Locosamide
Brivaracetam

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4
Q

Which anticonvulsants are 3A4 inducers?

A
Clobazam
Carbamazepine
Phenytoin
Oxcarbazapine
topiramate
Phenobarbital
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5
Q

Which anticonvulsants are 2C9 inducers?

A

carbamazepine

phenobarbital

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6
Q

Which anticonvulsants are 2C19 inducers?

A

carbamazepine
phenobarbital
phenytoin

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7
Q

Which anticonvulsants are 2C19 inhibitors?

A
eslicarbazepine
phenytoin
brivaracetam
locosamide
oxcarbazepine
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