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143 - Haemostasis and thrombosis > Anticoagulation Drugs > Flashcards

Anticoagulation Drugs Flashcards

1
Q

What is heparin?

A

This is an anti thrombin (FII) drug

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2
Q

What is LMWH

A

100 bioavailable heparin

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3
Q

What is heparin induced thrombocytopenia?

A

Type 1 - The postively charged heparin causes agglutination

Type 2 - SERIOUS - Get an immune response to the antibodies causing agglutination. DO NOT GIVE MORE PLATELETS OR HEPARIN

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4
Q

What is warfarin?

A

Vitamin K antagonist (2,7,9,10)

Not in pregnancy - teratogenic

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5
Q

Extras

A

Oral anti thrombin and anti Xa (Xaban)

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6
Q

Hirudins

A

From Leaches

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7
Q

When would you not give warfarin?

A

Pregnancy as it is teratogenic

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8
Q

What is the differnce between aspirin and clopidegrel?

A

Aspirin - Thromboxane A2 inhibitor for aggregation

clopidegrel - ADP antagonist for platelet and fibrin aggregation

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143 - Haemostasis and thrombosis (10 decks)

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