Anticoagulants Flashcards

1
Q

Médicaments contre indiqués en association avec des AVK

A
Aspirine
Ains
Colchicine
Allopurinol
Miconazole
CORTICOÏDES !!!
FQ
Phenylbutazone
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2
Q

Nom d.AVK

A

Warfarine
Fluindione
Acenocoumarol

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3
Q

Nom AOD

A

Dabigatran
Rivaroxaban
Apixaban
Edoxaban

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4
Q

Nom d’héparine

A
HNF
HBPM
Fondaparinux
Danaparoide 
Bivalirudine
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5
Q

Nom des thrombolytiques

A

Alteplase
Reteplase
Tenecteplase

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6
Q

Nom des anti agrégants plaquettaires

A
Aspirine ( kardegic. Apegic . Aspirine uspa)
Ticagrelor 
Prasugrel
Clopidogrel
Anti g2b3a
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7
Q

Syndrome de Widal

A

-> EI ASPIRINE
Asthme
Polypode naSo sinusienne
Intolérance AINS aspirine

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8
Q

Que met on comme médicament toujours en association à l’aspirine ?

A

IPP !!

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9
Q

Antidote HNF

A

Sulfate de protamine

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10
Q

Antidote du Dabigatran

A

Idacucizumab

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11
Q

Antidotes des AVK

A
Vitamine K (action en quelques heures)
PPSB (action rapide)
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12
Q

INR cible si Prothèse valvulaire mécanique

A

3-4

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13
Q

Examen obligatoire avant thrombolyse ?

A

GROUPAGE SANGUIN !!

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14
Q

Indications de thrombolyse

A

IDM de < 6-12h
AVC de < 4h30
EP grave
Thrombus dans le VD

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15
Q

Utilisables en cas d,insuffisance rénale (DFG <30)

A

AVK

HNF

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16
Q

Définition TIH

A

Chute plaquettes de > 40% sur 2 NFS successives

17
Q

Les 2 types de TIH

A

Type 1 🙂✅ PRÉCOCE - bénigne - pas de CI

Type 2 😡 GRAVE !!!
. J7-J10 ⏳: HNF (1 à 3%)
. Plusieurs semaines ⏳: HBPM (<1%)
=> IMMUNO ALLERGIQUE (Ac anti-complexe PF4) => CI A VIE
C°: CIVD
18
Q

Conséquences physiologiques d’une thrombopénie massive

A

ACTIVATION PLAQUETTAIRE
COAGULATION INTENSE
=> TVP /CIVD

19
Q

Acte non programmé / CHIR invasive sous anticoagulant

Quelle cible INR

A

<1,5
<1,2 si neurochir
=> Donner Vit K 5 mg
=> Si temps avant chir trop court: PPSB (=CCP)