anticholinergic and anticholinesterase drugs

Question 1

what is the dose of glycopyrrolate (Robinul)

Answer 1

0.015 mg/kg

Question 2

what is the onset of Robiul?

Answer 2

2-3 minutes (use with neostigmine)

Question 3

what is the dose of atropine?

Answer 3

0.03 mg/kg

Question 4

what is the onset of atropine?

Answer 4

1 minute (use with edrophonium)

Question 5

what is the dose of edrophonium (Enlon)?

Answer 5

0.5-1 mg/kg

Question 6

what is the onset of edrophonium?

Answer 6

30-60 sec

Question 7

what is the dose of neostigmine (Prostigmine?

Answer 7

0.06 mg/kg (max dose 5 mg)

Question 8

what is the onset of neostigmine?

Answer 8

7-11 minutes

Question 9

what is the dose of pyridostigmine?

Answer 9

0.3 mg/kg

Question 10

what is the onset of pyridostigmine?

Answer 10

10-20 minutes

Question 11

What is the dose of physostigmine?

Answer 11

0.5-2 mg/kg

• give slow
• for post op delirium

Question 12

What is the onset of physostigmine?

Answer 12

5 min

Question 13

What is the dose of scopolamine?

Answer 13

0.4 mg IM/IV

Question 14

What is the onset of scopolamine?

Answer 14

IV: 10 minutes
IM: 30-60 minutes

Question 15

What’s the dose of atropine for bradycardia?

Answer 15

0.015-0.070 mg/kg

Question 16

What’s the dose of physostigmine for CNS effects of atropine and scopolamine?

Answer 16

0.015-0.060 mg/kg

Question 17

What’s the dose a and onset of suggamadex?

Answer 17

2-4 mg/kg with 2/4 on TOF

Onset 1-3 minutes