Antibodies-->dz Flashcards

1
Q

anti-cardiolipin

A

Antiphospholipid syndrome

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2
Q

anti-centromere antibodies

A

specific for CREST–limited systemic sclerosis

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3
Q

anti-SCL-70 antibodies

A

assoc with diffuze Systemic sclerosis aka scleroderma— poor prognosis

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4
Q

Anticitrullinated peptide/protein antibodies

A

SPECIFIC for RA

RF is not specific for RA but is also (+)

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5
Q

(+) rheumatoid factor

A
  1. RA
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6
Q

anti-Jo-1

A

myositis specific

  • polymyositis
  • dermatomyositis
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7
Q

anti-signal recognition protein

A

Polymyositis

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8
Q

Anti-Mi-2

A

Dermatomyositis

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9
Q

AntiSS-A (Ro)

A
  • Sjogren

* SLE

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10
Q

Anti-SS-B (La)

A

Sjorgren

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11
Q

anti-double stranded DNA

A

SLE

  • specific not sensitive
  • also used to monitor dz
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12
Q

anti-smith antibodies

A

SLE

*speific not sensitive

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13
Q

antiphospholipid antibodies

A

incr risk of arterial or venous thrombosis

-esp pt with SLE

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14
Q

Lupus anticoagulant

A

Antiphospholipid antibody syndrome—SLE

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