Antibodies

Question 1

Anti dsDNA

Answer 1

SLE - specific

Question 2

Anti Yo

Answer 2

Paraneoplastic encephalitis with breast/ovarian cancer

Question 3

Anti NMDA

Answer 3

Paraneoplastic encephalitis with ovarian teratoma

Question 4

AQP4 ab or MOG ab

Answer 4

NMOSD

Question 5

Sjogren’s

Answer 5

Anti Ro

Anti La

Question 6

Anti U1RNP

Answer 6

Mixed CTD

Question 7

Anti mitochondrial

Answer 7

Primary biliary cirrhosis

Question 8

Anti Smooth Muscle

Answer 8

Autoimmune Hepatitis

Question 9

Anti Ma / Ta

Answer 9

Paraneoplastic encephalitis with testicular cancer

Question 10

Anti Scl70

Answer 10

Diffuse systemic sclerosis - a/w ILD

Question 11

Anti MuSK

Answer 11

Myasthenia Gravis - less ocular manifestations

Question 12

Anti Mi2

Answer 12

Dermatomyositis with skin lesions

Question 13

Anti THSD7A Ab

Answer 13

Membranous GN

Question 14

Anti VGCC

Answer 14

Lambert-Eaton Myasthenic Syndrome

Question 15

Anti-cardiolipin

Answer 15

APLS

Question 16

Neonatal Lupus

Answer 16

Anti-Ro

Question 17

Anti centromere

Answer 17

Limited systemic sclerosis, a/w with Pulmonary HTN

Question 18

Anti CCP

Answer 18

RA

Question 19

Anti histone

Answer 19

Drug-induced lupus

Question 20

Anti Sm

Answer 20

SLE - Highly specific

Question 21

Anti Hu

Answer 21

Paraneoplastic encephalitis with SCLC

Question 22

Anti PLAR2

Answer 22

Membranous GN

Question 23

Anti Jo1

Answer 23

Anti-synthetase syndrome

Question 24

Anti ribosomal P

Answer 24

SLE with neuropsychiatric manifestations

Question 25

Anti Ri

Answer 25

Paraneoplastic encephalitis with SCLC

Question 26

Anti LKM1

Answer 26

Autoimmune hepatitis Type 2

Question 27

Anti KELCH-11

Answer 27

Paraneoplastic encephalitis with testicular seminoma

Question 28

Anti-TIF1 gamma

Answer 28

Dermatomyositis - a/w malignancy

Question 29

RNA polymerase

Answer 29

Diffuse Systemic Sclerosis - a/w renal manifestations

Question 30

Anti-NXP2

Answer 30

Dermatomyositis - a/w malignancies

Question 31

Anti-SRP

Answer 31

Necrotising Autoimmune Myositis

Question 32

Anti-HMGCoA reductase

Answer 32

Necrotising Autoimmune Myositis

Question 33

Anti cN1A

Answer 33

Inclusion body myositis

Question 34

Anti MDA-5

Answer 34

Dermatomyositis - a/w ILD

Question 35

CD5 + CD19 expression

Answer 35

CLL

Question 36

Reed Sternberg cells

Which CD markers?

Answer 36

Hodgkin’s lymphoma

CD 15 / 30

Question 37

Plasma cells

Answer 37

CD38

Question 38

Stem cells

Answer 38

CD34

Question 39

Del 5q in what condition?

Answer 39

MDS

Treat with lenolidamide

Question 40

3 poor prognostic cytogenetic mutations in CLL?

Answer 40

Del 17p
Unmutated IGHV
tp53

Question 41

t(14, 18) -> what lymphoma?

Answer 41

Follicular lymphoma

Question 42

t(8,14) -> what lymphoma?

Answer 42

Burkitt’s

Question 43

t(11,14) -> what lymphoma?

Answer 43

Mantle cell