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FRACP NOSH 2020 > Antibodies > Flashcards

Antibodies Flashcards

1
Q

Anti dsDNA

A

SLE - specific

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2
Q

Anti Yo

A

Paraneoplastic encephalitis with breast/ovarian cancer

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3
Q

Anti NMDA

A

Paraneoplastic encephalitis with ovarian teratoma

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4
Q

AQP4 ab or MOG ab

A

NMOSD

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5
Q

Sjogren’s

A

Anti Ro

Anti La

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6
Q

Anti U1RNP

A

Mixed CTD

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7
Q

Anti mitochondrial

A

Primary biliary cirrhosis

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8
Q

Anti Smooth Muscle

A

Autoimmune Hepatitis

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9
Q

Anti Ma / Ta

A

Paraneoplastic encephalitis with testicular cancer

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10
Q

Anti Scl70

A

Diffuse systemic sclerosis - a/w ILD

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11
Q

Anti MuSK

A

Myasthenia Gravis - less ocular manifestations

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12
Q

Anti Mi2

A

Dermatomyositis with skin lesions

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13
Q

Anti THSD7A Ab

A

Membranous GN

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14
Q

Anti VGCC

A

Lambert-Eaton Myasthenic Syndrome

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15
Q

Anti-cardiolipin

A

APLS

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16
Q

Neonatal Lupus

A

Anti-Ro

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17
Q

Anti centromere

A

Limited systemic sclerosis, a/w with Pulmonary HTN

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18
Q

Anti CCP

19
Q

Anti histone

A

Drug-induced lupus

20
Q

Anti Sm

A

SLE - Highly specific

21
Q

Anti Hu

A

Paraneoplastic encephalitis with SCLC

22
Q

Anti PLAR2

A

Membranous GN

23
Q

Anti Jo1

A

Anti-synthetase syndrome

24
Q

Anti ribosomal P

A

SLE with neuropsychiatric manifestations

25
Anti Ri
Paraneoplastic encephalitis with SCLC
26
Anti LKM1
Autoimmune hepatitis Type 2
27
Anti KELCH-11
Paraneoplastic encephalitis with testicular seminoma
28
Anti-TIF1 gamma
Dermatomyositis - a/w malignancy
29
RNA polymerase
Diffuse Systemic Sclerosis - a/w renal manifestations
30
Anti-NXP2
Dermatomyositis - a/w malignancies
31
Anti-SRP
Necrotising Autoimmune Myositis
32
Anti-HMGCoA reductase
Necrotising Autoimmune Myositis
33
Anti cN1A
Inclusion body myositis
34
Anti MDA-5
Dermatomyositis - a/w ILD
35
CD5 + CD19 expression
CLL
36
Reed Sternberg cells Which CD markers?
Hodgkin's lymphoma CD 15 / 30
37
Plasma cells
CD38
38
Stem cells
CD34
39
Del 5q in what condition?
MDS Treat with lenolidamide
40
3 poor prognostic cytogenetic mutations in CLL?
Del 17p Unmutated IGHV tp53
41
t(14, 18) -> what lymphoma?
Follicular lymphoma
42
t(8,14) -> what lymphoma?
Burkitt’s
43
t(11,14) -> what lymphoma?
Mantle cell

FRACP NOSH 2020 (18 decks)

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