antibodies Flashcards
IgG shape
monomer
IgA shape
monomer / dimer
IgM shape
pentamer
IgD shape
monomer
IgE shape
monomer
IgG function
enhance phagocytosis of bacteria and viruses
fixes complement and passes to the fetal circulation
IgA function
provides localised protection on mucous membranes
most abundant isotype in blood serum
IgG
can pass to the fetal circulation
IgG
predominant immunoglobulin found in breast milk
IgA
where is IgA found
found in the secretions of digestive, respiratory, and urogenital tracts and systems
most commonly produced immunoglobulin in the body
IgA
transported across the interior of the cell via transcytosis
IgA
first immunoglobulin to be secreted in response to an infection
IgM
fixes complement but does not pass to the fetal circulation
IgM
anti-A, B blood antibodies
IgM
IgD function
role in immune system largely unknown
involved in activation of B cells
IgE function
mediates type I hypersensitivity reaction
binds to Fc receptors found on the surface of mast cells and basophils
provides immunity to parasites such as helminths
least abundant isotype in blood serum
IgE
mediates type I hypersensitivity reactions
IgE
binds to Fc receptors found on the surface of mast cells and basophils
IgE
provides immunity to parasites such as helminths
IgE
