Antibodies Flashcards
1
Q
C1q
A
Severe lupus, urticarial vasculitis
2
Q
dsDNA
A
High levels with SLE
Low levels with RA, Hashimotos, Graves, Waldenstroms, MCT, SSc, liver disease, SjS
3
Q
Histone
A
Drug induced LE
4
Q
Phospholipid
A
Primary APA, 50% SLE,
Drugs: cocaine, interferon, procainamide, hydralazine, phenothiazines, quinine, phenytoid
syphilis, TB, mono, leprosy, CMV, HIV, HCV
5
Q
rRNP
A
CNS disease witih LE
6
Q
Sm
A
Most specific antibody for LE
7
Q
ssDNA
A
Low diagnostic value
SLE in DLE patients, LINEAR MORPHEA IN KIDS
8
Q
U1RNP
A
MCTD, SLE
9
Q
SRP
A
Fulminant DM with cardiac involvement
10
Q
Mi-2
A
Good prognosis; skin only
11
Q
Jo-1
A
Interstitial lung, anti-synthetase syn, MECHANICS HANDS
12
Q
155kd/Se
A
Amyopathic DM; cancer
13
Q
Fodrin
A
Sjogrens
14
Q
SS-B
A
Sjogrens
15
Q
SSA (Ro)
A
Annular erythema of Sjogrens
Neonatal lupus
SCLE
