Antibodies Flashcards

1
Q

Anti-topoisomerase I

A

Systemic sclerosis (diffuse)

Also known as anti-Scl-70

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2
Q

Anti-RNA polymerase III

A

Systemic sclerosis (diffuse)

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3
Q

Anti-centromere

A

Systemic sclerosis (limited)

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4
Q

Anti-Jo-1

A

Polymyositis/dermatomyositis

Anti-synthetase antibody

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5
Q

Anti-Ro, Anti-La

A

Sjogren syndrome

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6
Q

Proteinase 3-ANCA/c-ANCA

A

Granulomatosis with polyangiitis (Wegener)

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7
Q

Myeloperoxidase-ANCA/p-ANCA

A

Eosinophilic granulomatosis with polyangiitis
Microscopic polyangiitis

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8
Q

Anti-U1 ribonucleoprotein

A

Mixed connective tissue disease:
Raynaud
Hand and finger swelling
Arthritis/synovitis
Inflammatory myopathy

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9
Q

Anti-Mi2

A

Dermatomyositis

Anti-helicase antibody

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10
Q

Anti-endomysial

A

Celiac

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