Antibodie functions Flashcards
Antibodies do not destroy antigens; they () and tag them
-Form antigen-antibody (immune) complexes
-Defensive mechanisms used by antibodies
-()
-Agglutination
-()
-() fixation
inactivate
Opsonization
Neutralization
Complement
() Antigen is inundated with antibody molecules
Allows for easier phagocytosis
opsonization
Antibodies can bind same receptor on two different antigens at the same time
Allows for antigen-antibody complexes to become cross-linked into large clumps
Example: clumping of mismatched blood cells
agglutination
-Antibodies block specific sites on viruses or bacterial exotoxins
-Prevent antigens from binding to receptors on tissue cells
-Antigen-antibody complexes undergo phagocytosis
neutralization
Main antibody defense against cellular antigens (bacteria, mismatched RBCs)
When several antibodies are bound close together on same antigen, complement-binding sites on their stem regions are aligned
-Complement binds to antibodies
-Leads to formation of (/) Complex (MAC) & cell lysis/death
Complement fixation
Membrane Attack