Antibodie functions Flashcards

1
Q

Antibodies do not destroy antigens; they () and tag them
-Form antigen-antibody (immune) complexes
-Defensive mechanisms used by antibodies
-()
-Agglutination
-()
-() fixation

A

inactivate
Opsonization
Neutralization
Complement

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2
Q

() Antigen is inundated with antibody molecules
Allows for easier phagocytosis

A

opsonization

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3
Q

Antibodies can bind same receptor on two different antigens at the same time
Allows for antigen-antibody complexes to become cross-linked into large clumps
Example: clumping of mismatched blood cells

A

agglutination

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4
Q

-Antibodies block specific sites on viruses or bacterial exotoxins
-Prevent antigens from binding to receptors on tissue cells
-Antigen-antibody complexes undergo phagocytosis

A

neutralization

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5
Q

Main antibody defense against cellular antigens (bacteria, mismatched RBCs)
When several antibodies are bound close together on same antigen, complement-binding sites on their stem regions are aligned
-Complement binds to antibodies
-Leads to formation of (/) Complex (MAC) & cell lysis/death

A

Complement fixation
Membrane Attack

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