Antibiotics Mode of Action Flashcards
Beta Lactams (Penicillins and Cephalosporins)
Inhibit bacteria cell wall biosynthesis
Aminoglycosides (Streptomycin, Neomycin, Kanamycin, Paromomycin)
Inhibit synthesis of proteins by bacteria, leading to cell death
Glycopeptides (Vancomycin, Teicoplanin)
Inhibit bacteria cell wall biosynthesis
Ansamycins (Geldanamycin, Rifamycin, Naphthomycin)
Inhibit synthesis of RNA by bacteria, leading to cell death
Streptogramins (Pristinamycin IIA, Pristinamycin IA)
Inhibit synthesis of proteins by bacteria, leading to cell death
Sulfanomides (Prontosil, Sulfanilamide, Sulfadiazine, Sulfisoxazole)
Prevent bacterial growth and proliferation. Look for sulfa allergy!
Tetracyclines (Tetracycline, Doxycycline, Limecycline, Oxytetracycline)
Inhibit synthesis of proteins by bacteria, preventing growth
Macrolides (Erythromycin, clarithromycin, azithromycin)
Inhibit protein synthesis by bacteria, occasionally leading to cell death
Oxazolidinones (Linezolid, Posizolid, Tedizolid, cycloserine)
Inhibit synthesis of proteins by bacteria, preventing growth
Quinolones (Ciprofloxacin, Levofloxacin, Trovafloxacin)
Interfere with bacteria DNA replication and transcription
Lipopeptides (Daptomycin, Surfactin)
Disrupt multiple cell membrane functions, leading to cell death