Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

peripheral vasodilators2 > antibiotics > Flashcards

antibiotics Flashcards

1
Q

aminoglycosides are

A

nephrotoxic, potentiate NDNMB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

clindamycin can induce

A

profound and long lasting neuromuscular block

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

vancomycin can cause

A

histamine release and hypotension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

sulfonamide is

A

highly protein bound and can increase plasma levels oral anticoag

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

common gram + organisms (4)

A

strep pyrogenes, strep pneumoniae, staph aureus, enterococcus faecalis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

common gram - bacteria (6)

A

klebsiella, enterobacter, pseudomonas, influenzae, gonorrhoe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

common anaerobes (2)

A

clostridium, bacteroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what does beta lactamase inhibitor do for pcn

A

increases spectrum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

pcn

A

gram positive cocci some gram neg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

pcn and cephalosporins

A

cross-sensitivity, bacteriocidal, beta lactam abx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

zosyn

A

pcn+beta lactamase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

zosyn coverage

A

many gram +, gram -, anaerobes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

ancef is a

A

1st gen cephalosporin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

ancef coverage

A

gram +, some gram -, clostridium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

third gen cephalosporin

A

rocephin- gram -, less gram +, inhibits cephalosporin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

as generation of cephalosporins increases

A

gram positivity coverage increases and more coverage against pseudomonas (3rd and 4th)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

4th gen cephalo

A

maxipime better gram +, more gram -, inhibit psudomonas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

2nd generation cephal

A

ceftin, more gram neg, similar gram +

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

preferred surgical prophylaxis, some cross bbb

A

cephalosporin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

carbepenems

A

(merrem, primaxin, invanz) broad, gram +, gram -, anaerobes

21
Q

aztreonam, aminoglycosides (gent)

A

aerobic gram - only

22
Q

vancomycin

A

gram + only

23
Q

gram + coverage only

A

vanco, clindamycin, macrolides

24
Q

clindamycin

A

gram + and anaerobes

25
Q

metrondiazole

A

anaerobic coverage only

26
Q

sulfonimides

A

some gram + and gram - coverage

27
Q

what drugs interfere with cell wall synthesis

A

vanco, pcn, cephalosporins

28
Q

what drugs inhibit bacterial protein synthesis

A

aminoglycosides, clindamycin

29
Q

quinolones are

A

cipro, levo- cover gram +, most gram -, chlamydia, legionalle, mycoplasm

30
Q

what do quinolones do

A

inhibit bacterial dna gyrase

31
Q

tetracyclines

A

aerobic, anaerobic, gram +, gram -

32
Q

aminoglycosides and tetracylcines

A

inhibit bacterial protein synthesis at the translational level

33
Q

polymixins

A

alter bacterial cell mem perm

34
Q

pcn, cphalosporins, vanco

A

interfere with synthesis of cell wall

35
Q

erythromycin and clindamycin moa

A

inhibit bacterial synthesis at the translational level

36
Q

sulfonamides

A

inhibit microbial sythesis of folic acid

37
Q

doxorubicin (adrianmyci) used in

A

breast, bladder, bronchhogenic ca, bone

38
Q

doxoruicin (adrianmycin) complications

A

causes cardiomyopathy, acute l vent failure during anesthesia. non spec st-t chances, svt, pvcs.

39
Q

symptoms dosoruicin cardiomyopathy

A

insidious with dry cough to heart failure that is unresponsive to inotropic drugs

40
Q

bleomycin used for

A

testicular ca

41
Q

serious side effect bleomycin

A

pulmonary toxicity- produces pulmonary endothelial damage to necrosis type 1 and proliferation of type 2 alveolar cells. interstitial fibrosis develops and may progress to whole lung.

42
Q

pt with lymphoma may dev

A

hyperthermia, hypotension, hypovolemia

43
Q

bleomycin anesthesia imp

A

fio2 <30%, replace fluids with colloids instead of crystalloids

44
Q

limit fio2 in pt taking

A

bleomycin or mitomycin

45
Q

elements mh

A

tacycardia, tachypnea, labile bp, risk etco2, masseter muscle spasm, acidosis, hyperthermia, tea colored urine, mottled skin

46
Q

late comp mh

A

cerebral edema, myoglobinuric renal failure, consumptive coagulopathy, hepatic dysfunction, pulm edema

47
Q

tx mh

A

call for help, hyperventilate 100% 02 at 10l, dantrolene 2.5mg/kg up to 10

48
Q

dantrolene 1/2 time

A

5-8 hours

peripheral vasodilators2 (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions