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Pharmacology > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

Natural penicillin w/ good oral bioavailability

A

Pen V

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2
Q

IV/IM administered natural penicillins

A

Pen G

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3
Q

Phenoxymethyl penicillin

A

Pen V

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4
Q

Benzyl penicillin

A

Pen G

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5
Q

aka Antistaphylococcal penicillins

A

Isoxazolyl penicillins

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6
Q

Prototype of Isoxazolyl penicillins

A

Methicillin (withdrawn due to nephrotoxicity)

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7
Q

penicillins w/ increased G (-) coverage and increased G (-) penetration

A

Extended spectrum penicillins

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8
Q

Amoxicillin, Ampicillin, and Bacampicillin are examples of what type of extended spectrum penicillins?

A

Amino penicillins

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9
Q

Carbenicillin and Ticarcillin are examples of what type of extended spectrum penicillins?

A

Carboxy penicillins

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10
Q

“PAM”

Piper, Azlo, and Mezlo (cillin) are examples of what type of extended spectrum penicillins?

A

Ureidopenicillins

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11
Q

Enumarate 4 sub classification of BETA LACTAM ANTIBIOTICS

CLUE: PCMC

A
  1. Penicillins
  2. Cephalosporins
  3. Monobactam
  4. Carbapenems
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12
Q

Type of extended spectrum penicillin w/ activity for Pseudomonas infections.

A

Carboxypenicillins like Carbe and Ticar (cillin)

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13
Q

Widest spectrum among beta lactam antibiotics

A

Carbapenems

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14
Q

Only monobactam

A

Aztreonam [only effective for aerobic G(-)]

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15
Q

Prophylaxis to the AE of vancomycin w/c is the red man syndrome

A

Diphenhydramine IV

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16
Q

Semisynthetic lipogylcopeptide derived from Vancomycin

A

Telavancin

17
Q

Semisynthetic lipogylcopeptide derived from teicoplanin

A

Dalbavancin

18
Q

2nd line agent for M. Tuberculosis resistant to the 1st line

A

Cycloserine

19
Q

Topical polypeptide

A

Bacitracin

20
Q

2 general types of antibiotics that inhibit 30S ribosomal subunit

A
  1. Tetracyclines

2. Aminoglycosides

21
Q

Chem structure: Naphthacene ring

A

Tetracycline

22
Q

Chem structure: large lactone ring

A

Macrolides

23
Q

Alternative to pxs allergic to B-lactam antibiotics

A

Macrolides

24
Q

“Methylated erythromycin”

A

Clarithromycin

25
Q

Macrolide w/ excellent distribution to body tissues + Longer half life + Once a day dosing only

A

Azithromycin

26
Q

Sulfated antibiotic

A

Lincosamides- Lincomycin

27
Q

Derma’s fave

Tx for skin and soft tissue infection caused by normal flora of the skin (staph and strep)

A

Clindamycin

28
Q

Ratio of streptogramins

A

70A:30B

A- Daltopristin
B- Quinapristin

29
Q

Chem: Isonicotinic hydrazide

A

Isoniazid (INH)

30
Q

Chem: PABA-like

A

Sulfonamides

31
Q

Sulfamethoxazole + Trimethroprim =

A

Cotrimoxazole

32
Q

Sulfadiazine + Pyrimethamine =

A

Darafrin

33
Q

Sulfadoxine + Pyrimethamine =

A

Fansidar

Pharmacology (6 decks)

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