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Module I > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

Mupirocin

A

inhibit Ile-tRNA synthase

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2
Q

Aminoglycosides (Streptomycin, Gentamycin, Neomycin, Tobramycin, etc.)

A

bind 30S subunit; inhibits initiation and causes miscoding during elongation

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3
Q

Tetracyclines

A

binds to 30S subunits and block attachment of charged aminoacyl-tRNA to the A site

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4
Q

Puromycin

A

resembles aa-tRNA (tyrosine analog), peptide transferred to it, chain termination (works on both prokaryotes and eukaryotes)

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5
Q

Macrolides (Erythromycin)

A

inhibits ribosomal translocation (erythromycin binds EF2)

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6
Q

Chloramphenicol

A

binds to 50S subunit and inhibits peptidyl transferase

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7
Q

Spectinomycin

A

binds to 30S subunits and block attachment of charged aminoacyl-tRNA to the A site

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8
Q

Clindamycin

A

inhibits ribosomal translocation

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Module I (9 decks)

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